[Assessment of safety of lyophilized substance of antibacterial peptide complex].

Aim: To assessment acute and chronic toxicity and local irritative effect of antibacterial peptide complex (ABC) substance extracted from interferon preparations.

Materials And Methods: Preclinical assessment of ABC substance was performed according to "Requirements for preclinical study of overall toxicity of new pharmacological substances".

Results: Series of experiments showed that single or prolonged (during 30 days) administration of ABC substance solution to mice intragastrically or rectally in maximal doses did not lead to death of experimental animals or pathological changes in their organs during pathomorphological and histological studies.