[Early Systolic Dysfunction of Left Ventricular Myocardium Is Reflected On Electrocardiogram of Patients With Aortic Stenosis].

Aim: to study relation between electrocardiographic (ECG) criteria of left ventricular hypertrophy (LVH) and parameters of tissue Doppler (TD) and LV strain in patients with aortic stenosis (AS) with preserved LV ejection fraction.

Material And Methods: We examined 80 patients with degenerative AS of all degrees of severity. Examination included history, blood serum cholesterol and creatinine, 12 lead ECG, routine echocardiography (EchoCG), TD, and LV global longitudinal peak strain (GLPS) in apical positions of 2-dimensional EchoCG.

[Arterial Hypertension Complicated by Myocardial Hypertrophy and Heart Failure Is Associated With Lower Serum Levels of Vascular Endothelium Growth Factor (VEGF-A165)].

Aim: To study relationships of serum levels of vascular endothelium growth factor with left ventricular (LV) myocardial hypertrophy (H) and signs of heart failure (HF) in patients with arterial hypertension (AH).

Methods: We examined 47 patients with AH and by echo established thickening ( more or equal 16 mm) of LV wall and 47 patients with AH and normal (<12 mm) thickness of LV wall from control group selected according to "head-to-head" principle by age and sex. Serum VEGF-A165 level was measured by sandwich solid-phase immunoenzyme assay.

[Degenerative aortic stenosis: prediction of poor prognosis by 2D left ventricular longitudinal strain in non-operated patients].

Aim: To investigate relationship between global longitudinal peak strain (GLPS) of the left ventricle (LV) and clinical routine echocardiographic (ECHO) and electrocardiographic (ECG) parameters in patients with non-operated aortic stenosis (AS) of all degrees. Also we evaluated the prognostic value of GLPS in patients with AS.

Methods: Patients with AS (n = 80) and control patients (n = 49) matched by age, sex and main cardio-vascular diseases were examined.