Profile and outcome of childhood tuberculosis treated with DOTS--an observational study.

Objectives: To study the clinical profile and outcome of childhood tuberculosis treated with Directly Observed Treatment Short (DOTS) course regimen. Also to study the side effects of anti-tubercular treatment (ATT).

Methods: This prospective hospital based observational study was conducted at Department of Pediatrics, Karnataka Institute of Medical Sciences (KIMS), Hubli.

Molecular basis of β-thalassemia in Karnataka, India.

In β-thalassemia, point mutations in the β-globin gene are largely responsible for either decreased or no β-globin synthesis. The β-globin gene has three exons and two introns. The molecular characterization of β-thalassemia is absolutely necessary for carrier screening, for genetic counseling, and to offer prenatal diagnosis.

Clinico-laboratory profile of pediatric HIV in Karnataka.

Objective: To study the clinical manifestations and incidence of opportunistic infections in HIV/AIDS seropositive proven hospitalized children.

Methods: Proven HIV seropositive children aged between 18 months to 12 years, admitted between April 2004 to June 2005 (15 months) to pediatric medical ward, KIMS, Hubli, were enrolled. Socio-demographic characteristics and clinical manifestations were recorded in the predesigned proforma.