Therapeutic efficacy of moxifloxacin and marbofloxacin against mastitis in buffalo.

Mastitis is a common economically important disease of dairy buffaloes. Antibiotic resistance is the most cited reason behind the failure of clinical mastitis treatment in buffaloes. Selection of antibiotic after antibiotic sensitivity test is the key to avoid multidrug resistance (MDR) for mastitis therapy.

Molecular detection and occurrence of contagious ecthyma in goat.

Contagious ecthyma or Orf is a common, contagious and zoonotic disease of small ruminants caused by orf virus. The present research was conducted to study the occurrence of Orf in goats in and around Parbhani district. Overall occurrence of Orf in goats was recorded 38.

Evaluation of IRF7 mRNA and its Association with Promoter Methylation in Kashmiri (North-Indian) Patients with Systemic Sclerosis: A Case-Control Study.

Introduction: The interferon regulatory factor 7 (IRF7), a member of the IRF family of transcription factors, plays a major role in the regulation of numerous aspects of an immune response and has increasingly been surveyed to determine the aetiology and pathogenesis of systemic sclerosis (SSc). Objective: This study aimed to investigate the transcriptional levels of IRF7 mRNA in peripheral blood mononuclear cells (PBMCs) and the impact of promoter methylation on IRF7 mRNA expression in SSc patients compared to healthy controls.

Methods: PBMCs were obtained from confirmed 40 naïve SSc cases and 20 healthy controls for IRF-7 expression and methylation analysis.