[Effect of an acute pharmacological test and a course of treatment with nifedipine on cerebral hemodynamic indices and information processing efficiency in hypertension patients].

Acute nifedipine tests and courses of nifedipine treatment were conducted in 30 patients with essential hypertension. The response of arterial blood pressure and cerebral hemodynamics to the acute test coincided with the results of a treatment course. The hypotensive effect, associated with nifedipine treatment, is combined with favorable cerebral hemodynamic changes and an increase in mental performance of hypertensive patients.

[Psychophysiological factors and their role in assessing the work capacity of arterial hypertension patients].

The homeostatic and information tests were used for the first time ever in addition to the MMPI method to evaluate the effects of psychophysiological factors on working capacity of 250 patients with arterial hypertensions and 127 normal subjects. Optimum performance in the solving of a homeostatic search problem was shown to be twice as rare in hypertensive patients, as compared to the normal subjects. A clear-cut relationship was established between the quality of information processing as evidenced by the information test, and the patients' psychological characteristics, BP values and the extent of cerebral hemodynamic changes.

[Changes in cerebral and central hemodynamics in response to hypotensive therapy of patients with essential hypertension and different types of circulation].

A study of indices of the cerebral and central hemodynamics in 122 patients with essential hypertension revealed differences in indices of the cerebral blood flow depending on the initial hemodynamic type. It was shown that the assessment of initial indices of the central hemodynamics makes it possible to achieve more favorable hemodynamic rearrangement, and an analysis of the cerebral hemodynamics--to foresee the inclusion of drugs correcting the cerebral blood flow in multimodality antihypertensive therapy.

[Interrelations between work capacity and the indicators of central and cerebral hemodynamics in patients with hypertension during hypotensive treatment].

The information test can provide an objective assessment of the working capacity of essential-hypertension patients in the course of treatment, as well as an indirect assessment of their cerebral flow. A correlation was demonstrated between the physical state of health and working capacity of hypertensive patients, on the one hand, and their arterial BP levels and severity of cerebral hemodynamic disorders, on the other, a fact to be considered in the administration of hypotensive treatment.