Publications by authors named "T A Mustafa"

Background: With the proportion of tuberculosis cases that are extrapulmonary tuberculosis (EPTB) increasing in recent years, understanding and addressing factors contributing to the prolonged time to diagnosis (TTD) of EPTB patients is vital.

Methods: We enrolled presumptive EPTB patients for a cohort study from 2018-2020 in Ujjain, India. Based on a structured questionnaire, the patients were interviewed for socio-demographic and clinical information, including previously visited health facilities (HF) for this illness.

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Background: To understand the impact of extrapulmonary tuberculosis (EPTB) and its treatment on quality of life, we analysed patient-reported outcome measures (PROMs) among presumptive ETPB patients.

Methods: EuroQol's five-dimensional three-level (EQ-5D-3L) questionnaire and the Visual Analogue Scale (EQ-VAS) were used to measure PROMs by 274 presumptive EPTB patients at pre- and post-treatment stages. The patients were categorised as TB and non-TB by using a composite reference standard.

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Article Synopsis
  • - The study evaluated plasma levels of ferritin, C-reactive protein (CRP), and adenosine deaminase (ADA) as biomarkers for monitoring treatment response in patients with extrapulmonary tuberculosis (EPTB), specifically those with TB lymphadenitis and TB pleuritis.
  • - Measurements were taken from 92 patients at the beginning of treatment, and again at 2 and 6 months, showing that elevated baseline levels of all three biomarkers significantly decreased after treatment.
  • - Results indicated that a combination of the three biomarkers could predict treatment response with high accuracy, achieving 83% at 2 months and 100% at 6 months, highlighting their potential as indicators of treatment effectiveness.
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The study aimed to isolate, purify and optimise tyrosinase from banana peel waste for industrial use. Tyrosinase was extracted from banana peel using phosphate buffer. Purification initiated with centrifugation followed by ammonium sulphate precipitation.

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Article Synopsis
  • The study assesses how combining various bioactive root-end filling materials with a composite bone graft influences healing in periapical tissues following endodontic microsurgery, using a triple-blinded clinical trial design.
  • 56 patients, aged 20 to 50 with specific dental issues, were randomly divided into two main groups based on root-end filling materials (MTA vs. TotalFill) and further split into subgroups with or without bone grafts.
  • After 12 months, the results showed no significant differences in healing or success rates across the groups, with no adverse effects reported.
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