Publications by authors named "T A Melton"

MicroRNAs are small noncoding nucleotides that serve as intracellular and extracellular signaling molecules. A previous collaboration found miR-127/3p circulation in the blood of breast cancer patients correlated with improved patient recovery and prognosis. While this study exclusively focused on breast cancer patients, data mining of the TCGA databases indicated that miR-127/3p may be positively associated with outcomes in other cancer types.

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Article Synopsis
  • The objective of the study is to analyze the pharmacodynamic and pharmacokinetic properties of cefepime-enmetazobactam (FEP-EMT) and present clinical evidence of its effectiveness, particularly for complicated urinary tract infections (cUTIs).
  • A comprehensive literature search from January 2015 to May 2024 was performed, which included various databases and types of studies, ultimately leading to the FDA approval of FEP-EMT for treating cUTIs following the successful Phase III ALLIUM trial against piperacillin-tazobactam (TZP).
  • FEP-EMT offers a promising alternative for treating infections caused by multidrug-resistant bacteria, but its limited effectiveness against certain tough pathogens
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Youth development researchers and practitioners share an interest in ensuring that youth development programs contribute positively to youth outcomes. Engaging in evaluation and data-informed decision making (DIDM) has the potential to empower practitioners to improve and adapt programs, improving youth outcomes. Yet, not all practitioners are comfortable engaging in evaluation and/or DIDM.

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The recent advent of quantum computing has the potential to overhaul security, communications, and scientific modeling. Superconducting qubits are a leading platform that is advancing noise-tolerant intermediate-scale quantum processors. The implementation requires scaling to large numbers of superconducting qubits, circuit depths, and gate speeds, wherein high-purity RF signal generation and effective cabling transport are desirable.

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