Limb salvage and functional recovery in infected nonunion of the distal tibia treated with the Ilizarov techniques.

Introduction: Treatment of infected nonunion of the distal juxta-articular tibia is a challenge due to a short distal fragment, deformity, thin soft-tissue envelope, and active infection. There is still no consensus on the approach that is able to maximally salvage the limb and ankle function.

Material And Methods: Infected juxta-articular nonunion of the distal tibia was managed with two Ilizarov techniques, monofocal compression (MC) used in 12 patients and bifocal compression-distraction (BCD) in 6 patients.

[Mathematical planning of the liquid-liquid extraction procedure: a forensic chemical study of verapamil in blood].

The objective of the study is to determine the optimal conditions for blood sample preparation by liquid-liquid extraction using mathematical planning of the experiment by the example of forensic chemical study of verapamil. Evaluation of verapamil recovery from blood samples was performed according to the scheme of multivariate three-level experimental planning using the Box-Behnken design. The effect of aqueous phase pH, the ratio of chloroform to -butanol in the extraction agent, extraction and centrifugation time, addition of sodium chloride, and the ratio of sample and extraction agent volumes on the recovery was studied.

Outcomes of revision arthroplasty for hip joint infection in matched groups of HIV-positive and HIV-negative patients....

Background: Several studies reported on periprosthetic infection after primary THA in HIV-positive patients, but very few showed the results of its revision.

Objective: The aim was to compare primary and secondary clinical outcomes after revision arthroplasty for hip joint infection in matched groups of HIV-infected and HIV-negative patients.

Methods: Using the hospital database, thirteen HIV-positive patients (13 infected hips) and thirteen HIV-negative patients of the matched control group (13 infected hips) were identified and their records were studied retrospectively.

[On the question of increasing the qualification of staff for the purposes of forensic-chemical and chemical-toxicological analysis: results of the questionnaire of expert chemists].

Today, one of the most effective tools for high-quality training of specialists at the postgraduate level is continuous professional development (CPD). Additional professional education of specialists in the field of forensic chemical and chemical-toxicological analysis with higher non-medical education (pharmaceutical, chemical, biological) is carried out on the basis of pharmaceutical and medical higher educational institutions, autonomous non-profit organizations through the implementation of additional professional training programs. The timing, forms, content and technology of training by organizations implementing the corresponding educational program are of great importance.

Ilizarov bone transport combined with the Masquelet technique for bone defects of various etiologies (preliminary results).

Background: The Ilizarov bone transport (IBT) and the Masquelet induced membrane technique (IMT) have specific merits and shortcomings, but numerous studies have shown their efficacy in the management of extensive long-bone defects of various etiologies, including congenital deficiencies. Combining their strong benefits seems a promising strategy to enhance bone regeneration and reduce the risk of refractures in the management of post-traumatic and congenital defects and nonunion that failed to respond to other treatments.

Aim: To combine IBT and IMT for the management of severe tibial defects and pseudarthrosis, and present preliminary results of this technological solution.