Eradication of proliferative verrucous leukoplakia with toll-like receptor 7 agonist (topical imiquimod): a case report.

Proliferative verrucous leukoplakia (PVL) is an aggressive and distinct type of oral precancerous lesion characterized by warty surfaced white plaque diffusely involving oral mucosa. Surgical excision is the treatment of choice. However, PVL has persistent and recurrent growth patterns, requiring multiple surgical procedures.

GOES-R Series X-Ray Sensor (XRS): 1. Design and Pre-Flight Calibration.

The X-Ray Sensor (XRS) has been making full-disk observations of the solar soft X-ray irradiance onboard National Oceanic and Atmospheric Administration's (NOAA) Geostationary Operational Environmental Satellites since 1975. Critical information about solar activity for space weather operations is provided by XRS measurements, such as the classification of solar flare magnitude based on X-ray irradiance level. The GOES-R series of XRS sensors, with the first in the series launched in November 2016, has a completely different instrument design compared to its predecessors, GOES-1 through GOES-15.

N4-Hydroxycytidine/molnupiravir inhibits RNA virus-induced encephalitis by producing less fit mutated viruses.

A diverse group of RNA viruses have the ability to gain access to the central nervous system (CNS) and cause severe neurological disease. Current treatment for people with this type of infection is generally limited to supportive care. To address the need for reliable antivirals, we utilized a strategy of lethal mutagenesis to limit virus replication.

Labor market pathways to job quality mobility in the service sector: Evidence from the "Great Resignation".

Since the mid-1970s, there has been a sharp rise in the prevalence of "bad jobs" in the U.S. labor market, characterized by stagnant wages, unstable work schedules, and limited fringe benefits.