Publications by authors named "T A Hide"
Article Synopsis
- Glioblastoma (GB) is highly invasive, and the study investigates the origins and molecular characteristics of butterfly glioblastoma (bGB) by analyzing a cohort of 34 bGB patients alongside others from public datasets.
- The results show that bGB can arise from two distinct origins—corpus callosum (CC) and cerebral hemisphere—with unique molecular mutations and prognostic implications, particularly identifying the CC-type as having worse survival outcomes.
- The study emphasizes the need for further research to understand the clinical significance and differences between the identified bGB subtypes to enhance treatment strategies and patient care.
Article Synopsis
- * This study investigated the use of focused shock waves to non-invasively release tumor-associated antigens from renal carcinoma cell lines, resulting in significant decreases in specific antigens on the cell surface.
- * Findings indicated that the shock waves and cavitation led to antigen release into extracellular spaces, with theoretical models developed to understand the mechanisms and cellular responses involved in this process.
Background: Craniotomy is required for the removal of brainstem cavernous malformations (CMs) with repeated hemorrhage, and this condition is often complicated by an accompanying developmental venous anomaly (DVA). However, a DVA of the brainstem or cerebellum with drainage penetrating the pons is an exceptional finding.
Observations: A 57-year-old man presented with double vision.
Background: This study investigated the factors influencing short-term survivors (STS) after gross total resection (GTR) in patients with IDH1 wild-type primary glioblastoma.
Methods: We analyzed five independent cohorts who underwent GTR, including 83 patients from Kitasato University (K-cohort), and four validation cohorts of 148 patients from co-investigators (V-cohort), 66 patients from the Kansai Molecular Diagnosis Network for the Central Nervous System tumors, 109 patients from the Cancer Genome Atlas, and 40 patients from the Glioma Longitudinal AnalySiS. The study defined STS as those who had an overall survival ≤ 12 months after GTR with subsequent radiation therapy, and concurrent and adjuvant temozolomide (TMZ).