Publications by authors named "T A Hammeke"

Article Synopsis
  • The study examines how common activities like caffeine consumption, sleep deprivation, and sleep aids affect the brain after mild traumatic brain injury (mTBI), suggesting these exposures can change brain function and structure during recovery.
  • Using an animal model, researchers analyzed brain changes through advanced imaging techniques after administering these treatments for 70 days following repeated mTBIs.
  • Results indicate that each treatment uniquely impacted brain regions, with sleep aids showing the most significant alterations, highlighting the importance of understanding everyday habits during recovery from mTBI.
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Little evidence exists about how mild traumatic brain injury (mTBI) is affected by commonly encountered exposures of sleep loss, sleep aids, and caffeine that might be potential therapeutic opportunities. In addition, while propofol sedation is administered in severe TBI, its potential utility in mild TBI is unclear. Each of these exposures is known to have pronounced effects on cerebral metabolism and blood flow and neurochemistry.

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Objective: Previous work using adaptive optics scanning light ophthalmoscopy (AOSLO) imaging has shown photoreceptor disruption to be a common finding in head and ocular trauma patients. Here an expanded trauma population was examined using a novel imaging technique, split-detector AOSLO, to assess remnant cone structure in areas with significant disruption on confocal AOSLO imaging and to follow photoreceptor changes longitudinally.

Methods And Analysis: Eight eyes from seven subjects with head and/or ocular trauma underwent imaging with spectral domain optical coherence tomography, confocal AOSLO and split-detector AOSLO to assess foveal and parafoveal photoreceptor structure.

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Article Synopsis
  • A subset of patients with mild traumatic brain injury (mTBI) report ongoing symptoms that negatively affect their daily lives, and identifying predictors of prolonged recovery could enhance clinical care and research for these individuals.
  • This study assessed various demographic, injury-related, and clinical factors in emergency department patients with mTBI and non-mTBI injuries to determine which variables best predict symptom duration during the recovery period.
  • Key findings indicated that factors like loss of consciousness, somatic symptom burden, and reaction time shortly after injury significantly predicted how long patients experienced symptoms, suggesting a need for a comprehensive approach to understanding recovery patterns in mTBI.
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Introduction: Children increasingly are being seen in the emergency department for a concussion, or mild traumatic brain injury (mTBI). A key aim of the ED visit is to provide discharge advice that can help parents to identify an evolving neurosurgical crisis, facilitate recovery, and prevent reinjury. The present study examined parents' knowledge of symptoms and recall of discharge instructions after their adolescent's mTBI and the effect of supplementing written discharge instructions with verbal instruction and reinforcement.

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