Mismatch repair system in colorectal cancer. Frequency, cancer phenotype, and follow-up.

Introduction And Aims: A frequent task in the study of colorectal carcinomas (CRC) is to identify tumors harboring deficient DNA mismatch repair systems (dMMR), which are associated with microsatellite instability. Given that there is scant information on those tumors in Mexican patients, our aim was to describe their frequency, clinical and pathologic characteristics, and results, which are necessary for future trials.

Materials And Methods: A consecutive series of CRC patients, treated and followed at a tertiary care center was performed.

Retrospective analysis of the clinical presentation and imaging of eight primary benign mediastinal schwannomas.

Objective: Mediastinal schwannomas are sometimes confused with other neoplasms during initial radiological studies, especially when there is a history of cancer in another area. In these cases, a more accurate analysis using computed tomography (CT) or even magnetic resonance (MRI) is required. Our study aimed to perform a retrospective analysis of the clinical and imaging features for a series of patients with mediastinal schwannomas that were confirmed by histology and immunohistochemistry.