Metabolic and immunologic aspects of fetoplacental insufficiency.

Problem: The chronic placental insufficiency is the most common cause of intrauterine hypoxia, retardation of fetal growth, and other threatening conditions. Immune disturbances may occur in the system "mother-placenta-fetus."

Method Of Study: Biochemical blood indicators were studied on an automated biochemical analyzer.

[Hygienic assessment of working conditions in the production of ferro-alloys].

This work is devoted to the study of conditions of the work of employees of the modern ferro-alloy production, which was performed in the framework of the evaluation of working places at the Open Joint-Stock Company «Ferrokhrom», which is part of Joint-Stock Transnational Company "Kazchrom". The studies were performed with account of the full range of the list of working places, both in the main and auxiliary shops. The work activity of the workers from leading professional groups was established to be conjugate of the impact of the complex of unfavorable factors of occupational environment and labor process.

Mutagenic and carcinogenic actions of chromium and its compounds.

Numerous experimental observations have been made on microorganisms and culture of the cells of mammals as well as the accounting of the chromosomal aberrations in the bone marrow cells of the mammals and of human cells displayed that the chromium and its compounds possess a pronounced mutagenic effect. Translocation test, induction record of DNA damage and repair systems in the mammalian and human cells with greater precision proves the presence of the mutagenic effect of the chromium and its compounds, which in turn is dependent on dose and time of this metal intoxication. Chromium and its compounds have pronounced mutagenic effect, on increased admission to organism of mammals and protozoa.

[Surgical policy in patients with chronic calculous cholecystitis complicated by choledocholithiasis].

Results of surgical treatment in 116 patients with chronic calculous cholecystitis complicated by choledocholithiasis were studied. Introduction in clinical practice of endoscopic papillosphincterotomy (EPST) and laparoscopic cholecystectomy changed surgical policy for benign combined lesions of gall bladder and extrahepatic bile ducts. Complex endoscopic treatment is preferable if contraindications are absent.