Publications by authors named "T A Blakely"
Background: Dynamic transmission models are often used to provide epidemiological guidance for pandemic policy decisions. However, how economic evaluation is typically incorporated into this technique to generate cost-effectiveness estimates of pandemic policy responses has not previously been reviewed.
Methods: We systematically searched the Embase, PubMed and Scopus databases for dynamic epidemiological modelling studies that incorporated economic evaluation of public health and social measures (PHSMs), with no date restrictions, on 7 July 2024.
Background: The Global Burden of Disease (GBD) 2021 study updated methods for attributing burden to physical inactivity, to include all conditions from fasting plasma glucose (FPG) due to physical inactivity. However, physical inactivity influences several additional GBD risk factors that also effect other diseases. This study estimated effects of physical activity on high blood pressure (hypertension), FPG (as diabetes), osteoporosis, and LDL-cholesterol, to enable mediation effects modelling.
View Article and Find Full Text PDFHealth gains from achieving optimal body mass index in Australia: a simulation study.
Lancet Reg Health West Pac
August 2024
Article Synopsis
- The study estimates the health benefits and inequality impacts of reducing body mass index (BMI) for the Australian population over the next 20 years and their lifetimes, projecting a potential gain of 2.00 million health-adjusted life years (HALYs) in the first two decades.
- It uses data from the 2017-2018 National Health Survey to model BMI's relationship with diseases, projecting that most health gains will come from reducing cardio metabolic diseases, with inequalities favoring the more deprived socio-economic groups.
- The findings highlight the significant potential for improving public health through BMI reduction and suggest that the modeling methods can be applied to assess other health interventions effectively.
To fully understand how the human brain works, knowledge of its structure at high resolution is needed. Presented here is a computationally intensive reconstruction of the ultrastructure of a cubic millimeter of human temporal cortex that was surgically removed to gain access to an underlying epileptic focus. It contains about 57,000 cells, about 230 millimeters of blood vessels, and about 150 million synapses and comprises 1.
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