Characterization of Sm-activated carbonated calcium chlorapatite phosphors for theranostic applications: a comparative study of co-precipitation and hydrothermal methods.

Continuous efforts are ongoing to discover new luminescent materials with appropriate properties for applications in medicine, serving as theranostic agents for healing and bioimaging. In this paper, novel single-phase carbonated calcium chlorapatite (Ca(PO)(CO)Cl, abbreviated as CaClAp-CO) phosphors activated with varying concentrations of Sm ions were successfully fabricated using both co-precipitation and hydrothermal methods to investigate the influence of the synthesis techniques on the physicochemical properties of these materials. The effects of doping concentration of Sm ions and synthesis techniques on the structure, photoluminescence (PL), energy transfer, substitute sites, fluorescence lifetime and luminescence colour of phosphors were investigated.

A Study of the Impact of Graphene Oxide on Viral Infection Related to A549 and TC28a2 Human Cell Lines.

Graphene has been one of the most tested materials since its discovery in 2004. It is known for its special properties, such as electrical conductivity, elasticity and flexibility, antimicrobial effect, and high biocompatibility with many mammal cells. In medicine, the antibacterial, antiviral, and antitumor properties of graphene have been tested as intensively as its drug carrying ability.

Quenching of the Eu Luminescence by Cu Ions in the Nanosized Hydroxyapatite Designed for Future Bio-Detection.

The hydroxyapatite nanopowders of the Eu-doped, Cu-doped, and Eu/Cu-co-doped Ca(PO)(OH) were prepared by a microwave-assisted hydrothermal method. The structural and morphological properties of the products were investigated by X-ray powder diffraction (XRD), transmission electron microscopy techniques (TEM), and infrared spectroscopy (FT-IR). The average crystal size and the unit cell parameters were calculated by a Rietveld refinement tool.

Strontium Phosphate Composite Designed to Red-Emission at Different Temperatures.

Eu-doped Sr(PO)(OH)-Sr(PO) (SrHAp-TSP) composites were obtained via the microwave-stimulated hydrothermal method and post-heat-treated from 750 to 950 °C. Concentration of the Eu ions was set to be 0.5, 1, 2, 3, 5 mol% in a ratio of the strontium ions molar content.

Structural modification of nanohydroxyapatite Ca(PO)(OH) related to Eu and Sr ions doping and its spectroscopic and antimicrobial properties.

The Eu and Sr ions co-doped hydroxyapatite nanopowders (Ca(PO)(OH)) were synthesized via a precipitation method and post heat-treated at 500 °C. The concentration of Eu ions was established in the range of 0.5-5 mol% to investigate the site occupancy preference.

The Comprehensive Approach to Preparation and Investigation of the Eu Doped Hydroxyapatite/poly(L-lactide) Nanocomposites: Promising Materials for Theranostics Application.

In response to the need for new materials for theranostics application, the structural and spectroscopic properties of composites designed for medical applications, received in the melt mixing process, were evaluated. A composite based on medical grade poly(L-lactide) (PLLA) and calcium hydroxyapatite (HAp) doped with Eu ions was obtained by using a twin screw extruder. Pure calcium Hap, as well as the one doped with Eu ions, was prepared using the precipitation method and then used as a filler.

A new approach to spectroscopic and structural studies of the nano-sized silicate-substituted hydroxyapatite doped with Eu ions.

Nanocrystalline silicate-substituted hydroxyapatites Ca10-xEux(PO4)4(SiO4)2(OH)2 (where x = 0.5, 1.0, 2.

Cytokines and cellular inflammatory sequence in non-athletes after prolonged exercise.

Aim: The goal of the study was to clarify the sequence of cytokines and inflammatory cells in non-athletes performed an intense running exercise.

Methods: Sixteen young healthy men participated in the exercise trial that involved 90-min run at 65% VO2max.

Results: The plasma concentrations of anti-inflammatory cytokines IL-4, IL-6 and IL-10 increased immediately after exercise simultaneously with number of white blood cells.

Changes of muscle-derived cytokines in relation to thiol redox status and reactive oxygen and nitrogen species.

The aim of this study was to compare the levels of the plasma muscle-derived cytokines (myokines) and reactive oxygen and nitrogen species (RONS) after muscle damage triggered by different exercises, and to demonstrate the relationships between RONS, thiol redox status and myokines. Sixteen young men participated in a 90-min run at 65% VO2max (Ex.1) or 90-min run at 65% VO2max finished with a 15-min eccentric phase (Ex.

Modulatory effect of N-acetylcysteine on pro-antioxidant status and haematological response in healthy men.

The aim of this study was to follow up whether the modification of pro-antioxidant status by 8-day oral application of N-acetylcysteine (NAC) in healthy men affects the haematological response, whether there is a direct relationship between antioxidant defences and erythropoietin (EPO) secretion and whether NAC intake enhances exercise performance. Fifteen healthy men were randomly assigned to one of two groups: control or NAC (1,200 mg d(-1) for 8 days prior to and 600 mg on the day of exercise trial). To measure the ergogenic effectiveness of NAC, subjects performed incremental cycle exercise until exhaustion.

Effects of sulphur-containing compounds on plasma redox status in muscle-damaging exercise.

The aim of the study was to compare effects of three-day N-acetylcysteine, alpha-lipoic acid or taurine administration on plasma antioxidant status and oxidative damage markers in healthy men after performing muscle-damaging exercise. Fifty-five healthy and trained men were randomly assigned to N-acetylcysteine (NAC, 1.8 g/day, 3 days), alpha-lipoic acid (ALA, 1.

The comparison of antioxidant and hematological properties of N-acetylcysteine and alpha-lipoic acid in physically active males.

The aim of this study was to follow up whether the modification of pro-antioxidant status by oral thiol administration such as N-acetylcysteine and alpha-lipoic acid affects the hematological response. Twenty-eight healthy men participated in two independent experiments. Subjects were randomly assigned to one of four groups: controls (C(NAC) and C(ALA)), N-acetylcysteine (NAC) and alpha-lipoic acid (ALA).

Pro-antioxidant ratio in healthy men exposed to muscle-damaging resistance exercise.

The purpose of this study was to compare the pro-antioxidant status in healthy men exposed to muscle-damaging resistance exercise, and to investigate the practical application of Loverro's coefficient (P/A ratio) to evaluate the presence of oxidative stress. Twenty-eight healthy men were assigned to two groups performed multi-joint (M) or single-joint (S) resistance exercise. The activities of superoxide dismutase (SOD), glutathione peroxidase (GPx) and catalase (CAT) as well as the concentration of lipid peroxidation products (TBARS) in blood were evaluated.

Effect of cysteine derivatives administration in healthy men exposed to intense resistance exercise by evaluation of pro-antioxidant ratio.

The aim of this study was to ascertain the influence of cysteine derivatives on pro-antioxidant equilibrium and to compare the antioxidant effectiveness of N-acetylcysteine, alpha-lipoic acid, and taurine by using Loverro's coefficient (pro-antioxidant ratio) in healthy men exposed to intensity-resistance exercise. Fifty-five men were randomly assigned to one of four groups: control (CON, placebo), N-acetylcysteine (NAC 1.8 g.

Oxidative stress in burnt children.

Background: One of the effects of burn injury is production of reactive oxygen species increasing general-structural damage. Such a condition is called oxidative stress. The purpose of this research was to find out whether oxidative stress is present in burnt children treated routinely and, if so, in which phase of the disease it is the most severe and how long it persists.

Prooxidant-antioxidant equilibrium in rowers: effect of a single dose of vitamin E.

Aim: The purpose of this research was to explain whether a single dose of vitamin E influences on disturbances of pro-oxidant-antioxidant equilibrium induced a laboratory 2,000 m rowing test.

Methods: The athletes were divided into two groups: vitamin E (1.000 mg alfa-tocopherol acetate) and P (placebo: cod-liver oil) supplemented 3 h before exercise.

The influence of atherogenic diet and "essential" phospholipids upon the contents of noradrenaline and dopamine in the brain of rats and their exploratory activity.

The influence of atherogenic diet and "essential" phospholipids (EPL) both on exploratory activity and catecholamine content in the brain of rats has been examined. The atherogenic diet caused a decrease of the animals' exploratory activity as well as a diminution of catecholamines. It was observed that these changes correlated.