[Assessment of cough threshold in patients with gastroesophageal reflux disease].

The aim of this study was the assessment of citric acid cough threshold in patients with chronic cough due to GERD, confirmed by 24-hour esophageal pH- monitoring, with other reasons of chronic cough excluded. Thirty subjects with chronic cough due to GERD and 15 healthy volunteers underwent cough challenge with doubling concentrations of citric acid using Asthma Provocation System (Jaeger). The cough threshold was defined as the first concentration of citric acid that induced cough.