Publications by authors named "Szunerits S"
Autologous or allogeneic platelet-derived extracellular vesicles (pEVs) show potential in enhancing tissue recovery and healing chronic wounds. pEVs promote neovascularization and cell migration while reducing inflammation, oxidative stress, and scarring. However, their efficacy in clinical settings is challenged by their susceptibility to washout by wound exudate.
View Article and Find Full Text PDFWe report the synthesis of multifunctional periodic mesoporous organosilica nanoparticles (PMO NPs) with substantial two-photon absorption properties and targeting capability for two-photon excitation fluorescence (TPEF) and photodynamic therapy (TPE-PDT). Prepared using an adapted sol-gel synthesis, the nanoplatforms integrated two silylated chromophores in their three-dimensional matrix to maximize non-radiative Förster resonance energy transfer from a high two-photon absorption fluorophore donor to a porphyrin derivative acceptor, leading to an enhanced generation of reactive oxygen species. Combinations of biodegradable and non-biodegradable bis(triethoxysilyl)alkoxysilanes were employed for the synthesis of the NPs, and the corresponding photophysical studies revealed high efficiency levels of FRET.
View Article and Find Full Text PDFExpression of concern for 'Near-infrared light activatable hydrogels for metformin delivery' by Li Chengnan , , 2019, , 15810-15820, https://doi.org/10.1039/C9NR02707F.
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- The study investigates the synthesis of nitrogen-doped carbon nanotubes (N-CNTs) using graphitic carbon nitride (g-C3N4) etching facilitated by nickel nanoparticles, highlighting innovative methods in nanotechnology.
- Concerns are raised regarding the growth processes and the implications for the quality and characteristics of the resulting N-CNTs, which are significant for various applications in electronics and materials science.
- The article emphasizes the need for further research to optimize the etching process and understand the interactions between g-C3N4 and nickel nanoparticles for better control over N-CNT synthesis.
Expression of concern for 'Clicking ferrocene groups to boron-doped diamond electrodes' by Manash R. Das , , 2009, 2753-2755, https://doi.org/10.
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- The article discusses the process and implications of localized electropolymerization on oxidized boron-doped diamond electrodes that have been modified with pyrrolyl units.
- It highlights the benefits of using such modified electrodes in various electrochemical applications.
- The expression of concern raises questions about the reproducibility and reliability of the results reported in the original study, suggesting the need for further investigation.
Expression of concern for 'An impedimetric immunosensor based on diamond nanowires decorated with nickel nanoparticles' by Palaniappan Subramanian , , 2014, , 1726-1731, https://doi.org/10.1039/C3AN02045B.
View Article and Find Full Text PDFExpression of concern for 'Reduced graphene oxide nanosheets decorated with AuPd bimetallic nanoparticles: a multifunctional material for photothermal therapy of cancer cells' by Gitashree Darabdhara , , 2015, , 8366-8374, https://doi.org/10.1039/C5TB01704A.
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- The paper discusses the use of plasmonic photothermal therapy for targeting uropathogenic bacteria using reduced graphene oxide and gold nanorods/rGO composites.
- An expression of concern has been published, addressing potential issues related to the methodology or data integrity in the research.
- Researchers are encouraged to critically review the findings and verify the results to ensure scientific accuracy and reliability.
Article Synopsis
- The article discusses the development of gold nanorods with a silica core-shell structure, which are enhanced with verteporfin, a photosensitizer used in photodynamic therapy.
- It emphasizes the high effectiveness of these nanostructures in the photodynamic inactivation of targeted cells or pathogens.
- The authors express concern regarding potential issues or limitations identified in the study, which may impact the reproducibility or applicability of the findings in clinical settings.
Expression of concern for 'Comparison of photo- and Cu(I)-catalyzed "click" chemistries for the formation of carbohydrate SPR interfaces' by Nazek Maalouli , , 2013, , 805-812, https://doi.org/10.1039/C2AN36272D.
View Article and Find Full Text PDFExpression of concern for 'Heat-based transdermal delivery of a ramipril loaded cream for treating hypertension' by Anna Voronova , , 2022, , 12247-12256, https://doi.org/10.1039/D2NR02295H.
View Article and Find Full Text PDFExpression of concern for 'Diamond nanowires modified with poly[3-(pyrrolyl)carboxylic acid] for the immobilization of histidine-tagged peptides' by Palaniappan Subramanian , , 2014, , 4343-4349, https://doi.org/10.1039/C4AN00146J.
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- The study explores a method using anti-fimbrial modified magnetic reduced graphene oxide nanoheaters to selectively target and eliminate bacteria responsible for urinary tract infections.
- Concerns are raised about the potential implications of this selective eradication approach, including its effectiveness and safety.
- The paper emphasizes the importance of understanding both the benefits and risks associated with such innovative treatments for infections.
Article Synopsis
- The paper discusses the potential of carbon quantum dots (CQDs) as a dual-function tool for both inhibiting collagen fibers and using light to destroy them, which could provide a new treatment for eye floaters.
- The authors express concern over the safety and efficacy of CQDs in this application, urging further research to fully understand their effects.
- This study highlights the implications of using nanotechnology in medical treatments, particularly in addressing common visual issues like eye floaters.
Expression of concern for 'Particle-based photodynamic therapy based on indocyanine green modified plasmonic nanostructures for inactivation of a Crohn's disease-associated strain' by Roxana Jijie , , 2016, , 2598-2605, https://doi.org/10.1039/C5TB02697K.
View Article and Find Full Text PDFExpression of concern for 'An 'on-demand' photothermal antibiotic release cryogel patch: evaluation of efficacy on an model for skin wound infection' by Léa Rosselle, , , 2020, , 5911-5919, https://doi.org/10.1039/D0BM01535K.
View Article and Find Full Text PDFExpression of concern for 'Anti-aggregation effect of carbon quantum dots on diabetogenic and beta-cell cytotoxic amylin and beta amyloid heterocomplexes' by Anna Voronova , , 2022, , 14683-14694, https://doi.org/10.1039/D2NR03173F.
View Article and Find Full Text PDFExpression of concern for 'Iron oxide magnetic nanoparticles with versatile surface functions based on dopamine anchors' by Mykola Mazur , , 2013, , 2692-2702, https://doi.org/10.1039/C3NR33506B.
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- Platelet extracellular vesicles (pEVs) from human platelets show promise in wound healing but have limited use in bandages; this research explores new hydrogel foams for their incorporation.
- The developed gelatine-based hydrogel (PAH-G) has good mechanical properties and can absorb high concentrations of pEVs, enhancing their therapeutic delivery.
- In tests on chronic wound healing in rats, treatment with the new hydrogel/pEV combination led to complete wound closure and improved healing dynamics, indicating their potential for personalized diabetic wound therapies.