Publications by authors named "Szu-Chieh Fu"

Background: Histological improvement and regression of liver fibrosis after long-term use of nucleos(t)ides analogues (NUCs) have been documented. The aim of the present investigation was to evaluate the usefulness of traditional sonography to detect hepatic and splenic changes during NUC therapy in chronic hepatitis B (CHB) patients.

Methods: A total of 181 CHB patients receiving NUC treatment were enrolled in this study.

View Article and Find Full Text PDF

Objectives: The protective effect of statins in cirrhosis and its decompensation in chronic hepatitis B (CHB) patients remains unknown.

Methods: We conducted a population-based cohort study using data from the Taiwanese National Health Insurance Research Database from 1997 to 2009. A total of 298,761 CHB patients were identified.

View Article and Find Full Text PDF

Background: The objectives of this study were to determine the in vitro anti-inflammatory and in vivo antihypertensive effects of fermented pepino (Solanum muricatum) milk by Lactobacillus brevis with the goal of developing functional healthy products. The inflammatory factors of fermented pepino milk with L. brevis were assessed in RAW 264.

View Article and Find Full Text PDF
Article Synopsis
  • A study was conducted in Taiwan using national health data to examine the impact of diabetes on cirrhosis in patients with chronic hepatitis C (CHC).
  • Among the 6,251 adult CHC patients analyzed, those who developed new-onset diabetes were found to have a significantly higher risk of developing cirrhosis and its decompensation compared to those without diabetes.
  • Diabetes was identified as an independent predictor for both cirrhosis and its worsening, even after adjusting for other health factors.
View Article and Find Full Text PDF

Background: The purpose of this study was to evaluate the functional potential of fermented pepino extract (PE) milk by Lactobacillus strains containing the glutamate decarboxylase (GAD) gene. Three Lactobacillus strains were selected, including L. brevis BCRC 12310, L.

View Article and Find Full Text PDF