Clinical evaluation of 24 h ambulatory monitoring of blood pressure under various environmental conditions (home and work versus hospital).

OBJECTIVE: To assess the effects of activity and environment on the spontaneous changes in 24 h blood pressure monitoring (BPM) and how these factors influenced the diagnosis of white-coat hypertension in the hypertensive subjects. PATIENTS AND METHODS: We examined 44 white-collar workers with untreated, uncomplicated mild hypertension, mean age 35 years, twice using 24 h BPM: on the day of natural activity, at home and at work (work-day 24 h BPM); and on the fourth day of hospitalization (hospital-day 24 h BPM). RESULTS: The mean value of blood pressure during activity period in hospital (hospital-day blood pressure) wqas significantly lower than that for ambulatory monitoring day (work-day blood pressure; 132/82 versus 138/85 mmHg).

[Dyslipoproteinemia in primary hypertension].

The aim of the study was the estimation of the lipid profile and prevalence of dyslipoproteinemia in patients with essential hypertension. The study group consisted of 108 outpatients (61 men and 47 women) with mild to moderate hypertension (HT), aged 35-64, who did not receive antihypertensive drugs for at least four weeks. The matched controls (MC) were randomly chosen for each HT patient from population of Warsaw inhabitants, covered by Pol-MONICA II screen.

[Plasma renin activity, aldosterone and adrenergic activity in patients with hypertension and in normotensives with a family history of hypertension].

Unlabelled: The aim of the study was to analyse plasma renin activity (PRA), aldosterone (Ald) and catecholamines at rest, after psychological stress and physical exercise in patients with essential hypertension (EH) and normotensive persons with (FH +) and without (FH-) family history of hypertension.

Materials And Methods: 100 men, aged 18-35 years, were investigated: 36 in EH, 32 in FH + and 32 in FH- groups. PRA, Ald and plasma level of adrenaline (A), noradrenaline (NA) and dopamine (D) were estimated at rest, after 30' of stress (Kraepelins test) and at the end and 30, after submaximal ergometric exercise.

Hypertension and lipids.

Hypertension and hyperlipidaemia are closely interrelated. Both belong to the most important risk factors of cardiovascular disease, with special emphasis on the premature development of atherosclerosis and its complications. The prevalence of both hypertension and hyperlidaemia is high; in the Polish adult population, like in many other countries, it amounts to 20-40% and 60-70%, respectively.

[Renovascular hypertension--clinical observations and long-term follow-up].

Renovascular hypertension is one of the most common causes of secondary hypertension. Its early diagnosis is particularly important, firstly because it is one of the few potentially reversible causes of chronic renal failure. In many centers, including our own, renal angioplasty (PTA) or surgery is the treatment of choice for patients with renovascular hypertension.

[Doxazosin (alpha 1-adrenoreceptor antagonist) used in primary hypertension and it's beneficial effect on lipid metabolism].

The aim of the study was to investigate the effect of a new selective alpha 1-adrenoreceptor blocker doxazosin on blood pressure, serum lipids and lipoproteins in patients with essential hypertension. The study was done in 32 out-patients with mild-to-moderate hypertension (22 men and 10 women, mean age 45.6 +/- 10.

[A difficult diagnostic case of malignant hypertension].

A case of a 62-year old male with malignant hypertension was described. The clinical picture was dominated by the presence of cachexia, polyuria and polyneuropathy. Laboratory examinations revealed highly elevated sedimentation rate, hyponatremia and hypokalemia.

[Comparative studies on the effects of propranolol and acebutolol on blood pressure, serum lipids and lipoproteins in patients with primary hypertension].

A comparative studies on the effect of propranolol and acebutolol on blood pressure, cardiac function, blood serum lipids and lipoproteins were carried out in 48 patients with the primary hypertension double-blind method was applied. Tested drugs were given for 12 weeks. It was found, that both drugs are potent and comparable hypotensive agents normalizing blood pressure in the majority of treated patients.

[Individual reactions and psychophysiologic reactions in patients with mild primary hypertension].

Fourteen male patients with mild hypertension, aged between 20 and 46 years (mean = 32.4 years) measured their arterial blood pressure thrice daily for 6 weeks. Prior to and after this period psychological tests were carried out, including Gough's ACL test and Spielberger's STAI questionnaire.

[Hypotensive effectiveness and metabolic effects of indapamide in patients with primary arterial hypertension].

Indapamide--a non-thiazide diuretic agent--was given to 28 patients with mild and moderate hypertension in a daily dose of 2.5 mg for 12 weeks. Statistically significant decrease in both systolic and diastolic blood pressure and complete normalization of the arterial blood pressure were achieved in 82% of the treated patients.

[Ambulatory 24-hour blood pressure monitoring in patients with resistant hypertension].

The aim of the study was to assess the usefulness of 24-hour blood pressure (BP) and heart rate (HR) monitoring in patients with "resistant" hypertension. 30 patients (44.1 +/- 9.

[Minipress in the treatment of arterial hypertension in light of results from a multicenter study. II. Results of long-term monotherapy].

Of 218 patients with arterial hypertension, who responded to monotherapy with prazosin (Minipress) during the first 3 months, 178 persons completed the 12-month treatment according to the study protocol. In 9 patients (4.1%) treatment was discontinued because of increase of blood pressure and/or side effects.

[Minipress in the treatment of arterial hypertension in light of results from a multicenter study. I. 3-month treatment: monotherapy versus combination treatment].

Multicenter study of the effectiveness and safety of prazosin (Minipress) in patients with arterial hypertension was carried out in 15 medical centers. Of 366 patients who entered the study, 328 persons satisfying all the protocol conditions were included into the final analysis. The treatment lasted 3 months.

[Twenty-four hour automatic recording of blood pressure and cardiac rhythm in patients with borderline hypertension].

The aim of the study was to evaluate the usefulness of 24-hour automatic recording of blood pressure and cardiac rhythm in patients with borderline hypertension. The study was performed in 50 patients aged 38.8 +/- 13.