[Laryngeal microsurgery in materials of Woiewódzki ENT department in Kalisz].

Basing on literature and own experience authors have presented possibilities and advantages this method. During 1994-1997 3239 patients were hospitalized, 249 because of larynx diseases. 88 (35.

[[Selected legal aspects related to medical practice].

The question of the physician's liability, both that of civil as well as penal law nature--is always emotionally approached. Dynamic development of medical and biological sciences as well as technics is the cause of progress but it also gives rise to the increase of hazards or abuses in medical therapy. If we speak of the therapeutic intervention being originally legal we mean that it is carried out in compliance with the principles of medical art.

[Congenital cholesteatoma of temporal bone].

On the basis of 72 reports in the literature and own case, the authors described new theories on the pathogenesis of congenital cholesteatoma. They present differentiation of congenital and acquired cholesteatoma by cyto-, histochemical and immunohistochemical methods. They discuss methods of diagnosis and therapy.

Insect neuropeptide leucopyrokinin analogues--synthesis and antinociceptive effect in rats.

The insect myotropic octapeptide leucopyrokinin Glp-Thr-Ser-Phe-Thr-Pro-Arg-Leu-amide (LPK or Lem-PK) (1) and its truncated analogues without the first N-terminal amino acids [2-8]-LPK (2) as well as devoid of the first, second and third N-terminal amino acids [4-8]-LPK (3) were prepared together with a series of the following modified [2-8]-LPK heptapetides such as: [Ala2] (4)-, [Ala3] (6)-, [D-Phe4] (7)-, [Ala5] (8)-, [D-Ala5] (9)-, [D-Thr5] (10)-, [Ser5] (11)-, [D-Pro6] (12)-, [Ala6] (13)- and [D-Arg7]-[2-8]-LPK (14) and [Pro1]-LPK (5). Bioassays were carried out by means of a hot-plate and a tail immersion tests in rats after i.c.

Women's health. Depression and related disorders.

Common mood disorders that are seen in women in primary care are major depression, dysthymic disorder, adjustment reaction with depressed mood, and premenstrual syndrome. This article reviews the diagnosis and treatment of major depression, which also are applicable in many ways to other mood disorders. Specifics about other mood disorders that are encountered frequently in women are discussed subsequently.

Autologous fat injection into the vocal folds: technical considerations and long-term follow-up.

Numerous materials have been used over the years for vocal fold augmentation. Early use of bioreactive compounds, such as paraffin, gave way to relatively inert substances, such as Teflon. More recently biocompatible materials, such as collagen and autologous fat, have gained wider acceptance.

Absence of sex differences in the evaluation of patients hospitalized for transient ischemic attacks.

Background: Sex has been shown to affect the extent of evaluation and treatment of patients with coronary artery disease. This study investigates potential differences in the evaluation of hospitalized men and women with transient ischemic attacks to determine whether a similar bias exists.

Methods: The 1989 MedisGroups comparative database was used to analyze a convenience sample consisting of all family and internal medicine patients with the primary admission diagnosis-related group (DRG) of "transient ischemic attack.

Role of lysine 173 in heparin binding to heparin cofactor II.

Heparin cofactor II (HC) is a plasma serine proteinase inhibitor (serpin) that inhibits alpha-thrombin in a reaction that is dramatically enhanced by heparin and other glycosaminoglycans/polyanions. We investigated the glycosaminoglycan binding site in HC by: (i) chemical modification with pyridoxal 5'-phosphate (PLP) in the absence and presence of heparin and dermatan sulfate; (ii) molecular modeling; and (iii) site-directed oligonucleotide mutagenesis. Four lysyl residues (173, 252, 343, and 348) were protected from modification by heparin and to a lesser extent by dermatan sulfate.

[Osteoplastic tracheopathy].

Review of literature and the own case was presented. The symptoms, diagnosis and treatment were described.

Outbreak of itching and rash. Epidemic hysteria in an elementary school.

Fifty-seven of 159 rural elementary school students had an explosive spread of pruritus and rash--a rarely described manifestation of epidemic hysteria. In a sample of 13 children (23%), each child examined had irregular, macular, erythematous lesions that were excoriated and actively changed during examination. Rash occurred only at sites readily accessible to hands.