Publications by authors named "Szeto M"

Objective: The authors sought to examine the association between the increased use of videoconferencing and image-enhancing software filters during the COVID-19 pandemic and the corresponding rise in interest in cosmetic procedures. We aimed to discern if heightened exposure to one's digital self-image correlates with a greater inclination toward cosmetic interventions.

Methods: In this cross-sectional questionnaire survey study, adult participants living in the United States were recruited on Amazon's Mechanical Turk platform.

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Article Synopsis
  • The Global Burden of Disease (GBD) study focuses on understanding the worldwide prevalence and impact of significant diseases.
  • PatientsLikeMe (PLM) is an online platform where patients share their experiences, offering valuable insights into health conditions.
  • A comparison of data from GBD and PLM for dermatologic conditions showed both expected demographic differences and surprising correlations, suggesting that these data sources can work together to highlight unmet patient needs and priorities.
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Background: Influenza pandemic plans often recommend non-pharmaceutical interventions (NPIs) in household settings, including hand hygiene and face masks. We reviewed evidence supporting the recommendations of these measures to prevent the spread of influenza in households.

Methods: We performed systematic reviews between 26 May and 30 August 2022 in Medline, PubMed, EMBASE, and CENTRAL to identify evidence for the effectiveness of selected measures recommended by representative national influenza pandemic plans.

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TikTok is a social media platform that can educate users about dermatology, but this longitudinal analysis of skin of color-related TikTok hashtags from 2021 to 2022 suggests that nondermatologist influencers continue to dominate content creation, highlighting the need for more participation from board-certified dermatologists to actively counter misinformation and address potential disparities in skin-of-color health care.

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Analyses of women dermatology literature authorship from 2018 to 2022 reveal a slight increase in total female authors, female first authors, and female senior authors with no substantial immediate impact of COVID-19 on current trends, encouraging future examination of long-term effects and ongoing promotion of systemic initiatives to support gender equity.

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Online patient-oriented platforms such as PatientsLikeMe (PLM) offer a venue for individuals with various diagnoses to share experiences and build community, though they may not be representative of the larger patient population. This potentially limits generalizability and raises concerns about the spread of misinformation, emphasizing the need for informed use and health care provider engagement.

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Importance: Whether stereotactic body radiotherapy (SBRT) as a bridge to liver transplant for hepatocellular carcinoma (HCC) is effective and safe is still unknown.

Objective: To investigate the feasibility of SBRT before deceased donor liver transplant (DDLT) for previously untreated unresectable HCC.

Design, Setting, And Participants: In this phase 2 nonrandomized controlled trial conducted between June 1, 2015, and October 18, 2019, 32 eligible patients within UCSF (University of California, San Francisco) criteria underwent dual-tracer (18F-fluorodeoxyglucose and 11C-acetate [ACC]) positron emission tomography with computed tomography (PET-CT) and magnetic resonance imaging (MRI) with gadoxetate followed by SBRT of 35 to 50 Gy in 5 fractions, and the same imaging afterward while awaiting DDLT.

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Article Synopsis
  • - The study highlights that women continue to be underrepresented in leadership roles within academic dermatology, particularly on editorial boards of leading journals
  • - It stresses the importance of addressing this imbalance to enhance diversity, equity, and inclusion in the field
  • - The research calls for the development and implementation of proactive strategies to improve gender representation in these influential positions
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This research letter assesses male skin care content on social media in order to bring to light the lack of content regarding skin cancer prevention posted on Instagram for male audiences.

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  • Seborrheic dermatitis (SD) is common in people with Parkinson's disease (PD), affecting 18.6%-59%, and oral cannabidiol (CBD) may help reduce both sebum production and PD symptoms.
  • This study explores the potential benefits of CBD in decreasing the severity of SD in PD patients through a randomized, double-blind, placebo-controlled trial.
  • Results showed no significant treatment effect on SD severity between CBD and placebo groups, but there was a trend indicating improvement in the CBD group and worsening in the placebo group, suggesting further research is needed.
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Prurigo nodularis (PN) is an intensely pruritic, inflammatory skin disease with a poorly understood pathogenesis. We performed single-cell transcriptomic profiling of 28,695 lesional and nonlesional PN cells. Lesional PN has increased dysregulated fibroblasts (FBs) and myofibroblasts.

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Actemra (tocilizumab) received emergency use authorization for the treatment of coronavirus disease 2019 (COVID-19) in June 2021. Literature has linked numerous cutaneous adverse effects to tocilizumab. In this current survey, investigators reviewed and compared these adverse effects to the common cutaneous manifestations of COVID-19.

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Background: Skill competency assessments induce stress and anxiety and may affect nursing student performance. Little is known about stress and perceived anxiety levels and their relationship in the mock skill competency assessment.

Methods: A cross-sectional study was conducted to examine the stress levels (as assessed by heart rate variability, HRV) and perceived anxiety before, during and after the mock skill competency assessment, and to explore their relationships to performance in a total of ninety first-year undergraduate nursing students.

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Article Synopsis
  • Prurigo nodularis (PN) is a chronic skin condition mainly affecting African Americans, characterized by itchy nodules and a poorly understood cause.
  • Researchers performed whole-exome sequencing on skin samples from PN and atopic dermatitis patients, discovering significant mutations in genes related to fibrotic and neurotropic processes, particularly in the Notch signaling pathway.
  • The study highlights a link between altered Notch signaling and PN, revealing new insights into its pathophysiology and increased risks for associated diseases in PN patients.
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  • Young adults are feeling pressure to have an attractive athletic body, heavily influenced by social media platforms like Instagram.
  • This pressure often leads to body image dissatisfaction and increased use of anabolic-androgenic steroids (AAS) to achieve these aesthetic goals.
  • Dermatological issues, such as acne and severe forms like acne fulminans, should be recognized as potential signs of AAS abuse, prompting dermatologists to address these concerns to better support their patients' health.
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Prurigo nodularis (PN) is an understudied inflammatory skin disease characterized by pruritic, hyperkeratotic nodules. Identifying the genetic factors underlying PN could help to better understand its etiology and guide the development of therapies. In this study, we developed a polygenic risk score that predicts a diagnosis of PN (OR = 1.

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Background: The prioritisation of updating published systematic reviews of interventions is vital to prevent research waste and ensure relevance to stakeholders. The consideration of health equity in reviews is also important to ensure interventions will not exacerbate the existing inequities of the disadvantaged if universally implemented. This study aimed to pilot a priority setting exercise based on systematic reviews of interventions published in the Cochrane Library, to identify and prioritise reviews to be updated with a focus on health equity.

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Background: In cosmetic dermatology, lasers and lights treat a variety of hair and skin conditions, including some that disproportionately affect people of color.

Aims: Our systematic review aims to understand the representation of participants with skin phototypes 4-6 in cosmetic dermatologic trials studying laser and light devices.

Methods: A systematic literature search was conducted using search terms "laser," "light," and multiple laser and light subtypes in the PubMed and Web of Science databases.

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Background: Modern pediatric anesthetic encounters occur in operating rooms and non-operating room settings. Most anesthesia providers have cared for children in radiology, endoscopy, and other interventional settings at some point in their training and career. There is an absence of published data on the frequency, timing, and demographics of these pediatric anesthesia encounters.

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