Towards robotic laboratory automation plug & play: Reference architecture model for robot integration.

Supportive robotic solutions take over mundane, but essential tasks from human workforce in biomedical research and development laboratories. The newest technologies in collaborative and mobile robotics enable the utilization in the human-centered and low-structured environment. Their adaptability, however, is hindered by the additional complexity that they introduce.

WITHDRAWN: Towards robotic laboratory automation Plug & play: Survey and concept proposal on teaching-free robot integration with the lapp digital twin.

The Publisher regrets that this article is an accidental duplication of an article previously published at http://dx.doi.org/10.

Towards robotic laboratory automation Plug & play: Survey and concept proposal on teaching-free robot integration with the lapp digital twin.

The Laboratory Automation Plug & Play (LAPP) framework is an over-arching reference architecture concept for the integration of robots in life science laboratories. The plug & play nature lies in the fact that manual configuration is not required, including the teaching of the robots. In this paper a digital twin (DT) based concept is proposed that outlines the types of information that must be provided for each relevant component of the system.

Towards robotic laboratory automation Plug & Play: The "LAPP" framework.

Increasing the level of automation in pharmaceutical laboratories and production facilities plays a crucial role in delivering medicine to patients. However, the particular requirements of this field make it challenging to adapt cutting-edge technologies present in other industries. This article provides an overview of relevant approaches and how they can be utilized in the pharmaceutical industry, especially in development laboratories.

Does carbamazepine-epoxide conjugate with glutathione? On an existing but almost forgotten possibility.

The anticonvulsant carbamazepine is widely used to treat affective disorders and behavioural disorders in non-epileptic children. We report an elevated plasma level of carbamazepine-10,11-epoxide in a cystinuric child after daily medication with 300 mg carbamazepine while the serum level of carbamazepine was in the therapeutic range. The concentrations of carbamazepine and its epoxide derivative were determined by HPLC.

[Ethical questions concerning organ transplantation, with special reference to Great Britain].

Although the cousience and character of a good doctor are sufficient on their own to allow us to discuss and make decisions regarding very difficult ethical subjects in transplantation, basic ethical principles commonly used in medicine must also be applied to various aspects of organ donation. Some system has to be adopted that assesses the weight that must be given to various possible solutions. For example, would live donor transplantation still be acceptable if there were a surfeit of cadaveric organs? If animal organs can be transplanted successfully, is that more desirable than using human organs: particularly if human donation involves interventional ventilation or non-heart beating donors? Is interventional ventilation more "ethical" than live donor liver or lung transplantation? No doubt future developments in transplantation, opening more opportunities for the successful treatment of more patients, are likely to produce increasingly difficult ethical issues.

Cholecystectomy through a mini laparotomy alongside laparoscopic technique.

The authors present the surgical treatment of gallstones with special instruments and technique through a mini laparotomy, as developed in Kaposvár (Hungary). Despite the fact that the widespread use of laparoscopic cholecystectomy (LC) has succeeded over open cholecystectomy (OC), in their opinion, there are some instances where cholecystectomy through a mini laparotomy (MLC) would be advantageous. Last year (1996), in the authors' department, 32 MLCs were performed in addition to 72 OCs and 176 LCs.

Thoracic and lumbar sympathectomy with the application of ROMICRO mini laparotomy set.

The authors present the use of ROMICRO set (originally developed for mini laparotomy) for thoracic and lumbar sympathectomy. They review 3 thoracic and 2 lumbar sympathectomy operations that had good effects and uneventful recoveries. The advantage of the method is that no special instruments are needed and it can be done as a conventional operation.

[The lecture].

The author reviews the rules of conduct to be followed in lectures and he identifies a number of advices, useful for young colleagues. The fundamental ethical goal of lectures is to serve the audience as well as possible. The author touches upon the most important general rules of oral communications such as punctuality, discipline of remaining within time limitations, but he also describes advices how to work and deliver talks lectures.

Local anaesthesia and inguinal hernia repair: a cautionary tale.

Two patients undergoing inguinal herniorrhaphy developed transient quadriceps paresis after local inguinal nerve block. One sustained a compound fracture of the distal tibia and fibula. The importance of warning the patient and of increasing the awareness of nursing staff to the possibility of quadriceps weakness after use of local anaesthetic is emphasised.

[Major theoretical and practical aspects of publications].

The author discusses some ideas concerning the sharing of scientific informations. The fundamental goal of the latter is to serve the readers as perfectly as possible. A physician of research ambitions may valuable contribute to the progress of applied sciences but this must not jeopardize the medical care of the patients.

[Gallbladder torsion in infants].

The infrequent case of gallbladder torsion and accompanying Meckel's diverticulum in a 3-year-old girl, is described. Detorquation, cholecystectomy and resection of the diverticulum were performed. Condition of the development of the disease as well as its clinical aspects and therapy are discussed.

[Classification of polytraumatized patients, experience with the ISS system].

Authors assessed the process of healing of 161 polytraumatized patients from 1976- to 1987, treated intersively, using the ISS system. Mortality was 27 per cent. Independently from the ISS system the concomittant shock foretold invariably a bad prognosis, although this was also joined generally to a big point number.

Osmotic characteristics of sheep and cattle embryos.

Ten minutes of exposure to increasing concentrations of sucrose caused a proportional decrease in the volume of sheep late morulae, their relative volume changed as a linear function of the reciprocal of the osmolality of the medium. Day 6 sheep and Day 7 cattle embryos responded to the addition of permeating cryoprotectants by an initial shrinkage which was followed by gradual reexpansion. After 1.