Publications by authors named "Sze C Chan"
Objectives: Adrenal gland cancer (AGC) is a rare cancer with a poor prognosis. Studies on this cancer have been limited. This study, for the first time, aims to analyse the global disease burden and trends of adrenal gland cancer in country level and examine lifestyle and socioeconomic risk factors to generate hypotheses.
View Article and Find Full Text PDFBackground: Globally, pancreatic cancer poses a significant concern for public health.
Aims: The objective of this study was to assess the burden of pancreatic cancer on varying income levels.
Methods And Results: Data from the Global Burden of Disease Study (GBD) 2021 and Gross Domestic Product Per Capita data were utilised in this study.
Article Synopsis
- - The study investigates obesity prevalence among children in Hong Kong, focusing on primary and secondary school students, and aims to identify associated risk factors linked to sociodemographic and health-related behaviors.
- - Data was gathered through self-administered surveys from nearly 5,000 students across 55 schools, revealing that obesity is more common in male students, particularly those with poor academic performance and unhealthy lifestyle habits, like high sugary drink consumption and low physical activity.
- - Key findings suggest that male gender, inactivity, low self-esteem in academics, and poor dietary choices are significant risk factors for obesity, underlining the need for targeted interventions for at-risk youth and further research on effective solutions.
Objective: This study aimed to investigate the incidence, risk factors and trends for vaginal cancer.
Design: Retrospective observational design.
Setting: Data were collected from multiple sources, including the Global Cancer Observatory, Cancer Incidence in Five Continents Plus, Global Burden of Disease, World Bank and the United Nations.
Background: Ureteral cancer is a rare cancer. This study aimed to provide an up-to-date and comprehensive analysis on the global trends of ureteral cancer incidence and its association with lifestyle and metabolic risk factors.
Methods: The incidence of ureteral cancer was estimated from the Cancer Incidence in Five Continents Plus and Global Cancer Observatory databases.
Background: Non-Hodgkin lymphoma (NHL) accounts for 90% of all malignant lymphomas. This study aimed to evaluate the global incidence, mortality, associated risk factors, and temporal trends of NHL by sex, age, and country.
Methods: Data from 185 countries globally were used for analysis.
Background And Aims: Unhealthy diets were found to be the main contributor to the overweight problem among adolescents. In this study, we aim to identify the factors causing unhealthy eating habits in adolescents.
Methods: School-aged children and adolescents participated in this cross-sectional observational study with additional school and parental consent.
Background: This study aims to investigate the global disease burden, risk factors, and temporal trends of eye cancer by sex and age group.
Methods: Databases including Cancer Incidence in Five Continents volumes I-XI, the Nordic Cancer Registries, the Surveillance, Epidemiology, and End Results Program and the WHO IARC mortality database were accessed to extract incidence and mortality data. Joinpoint regression analyses were conducted to evaluate the Average Annual Percentage Change of the incidence and mortality.
Background: A significant proportion of young people do not respond to the NICE recommended treatment for anorexia nervosa: Family Therapy. Whilst historically these young people would be admitted to inpatient services, which are associated with greater treatment cost, greater risk of relapse, and worse outcome, more recently evidence is building for the effectiveness of day programmes. One day programme that has been found to be effective is the Intensive Treatment Programme (ITP) of the Maudsley Centre for Child & Adolescent Eating Disorders in London, UK.
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- - The study investigates the global epidemiological trends of laryngeal cancer, which, despite being rare (only 1% of total cancers), has a high prevalence among head and neck cancers.
- - Data from multiple sources showed that the age-standardized incidence and mortality rates are low overall, but regions like the Caribbean and Central/Eastern Europe exhibit higher rates, with tobacco and alcohol consumption identified as key risk factors.
- - Although the global incidence of laryngeal cancer is decreasing, particularly among men, increasing rates in females and younger individuals suggest disparities, warranting further research into access to treatment and other influencing factors.
Objectives: To examine the global disease burden and country-specific trends of penile cancer incidence by age group and investigate its associations with several factors.
Materials And Methods: The Global Cancer Observatory database was interrogated for penile cancer incidence. The 10-year cancer incidence rates were collected from the Cancer Incidence in Five Continents Plus.
Background: Health literacy is essential in the promotion of healthy lifestyle habits and chronic disease prevention.
Objective: To assess the health literacy level among Hong Kong adolescents; to evaluate the association between access of an online health information platform (GoSmart Channel) and health literacy level; and to examine the association between health literacy level and various unhealthy behaviours.
Design: This study recruited students from 10 local secondary schools in Hong Kong to assess the health literacy level among adolescents.
Background: Worldwide, gastric cancer is a leading cause of cancer incidence and mortality. This study aims to devise and validate a scoring system based on readily available clinical data to predict the risk of gastric cancer in a large Chinese population.
Methods: We included a total of 6,209,697 subjects aged between 18 and 70 years who have received upper digestive endoscopy in Hong Kong from 1997 to 2018.
Aim: To investigate the risk factors associated with physical inactivity of young children in Hong Kong.
Methods: This follow-up study was part of a prospective cohort study named Studying Impact of Nutrition on Growth (SING) initiated in 2015. Subjects were recruited from randomly selected local nurseries and kindergartens in Hong Kong.
Article Synopsis
- Vulvar cancer is a rare but significant health issue due to its diagnostic and treatment costs, as well as its impact on women's mental health.
- The study analyzes global vulvar cancer incidence trends and risk factors, revealing higher rates in regions like Western Europe and Northern America, with socioeconomic factors contributing to increased cases.
- The incidence is rising overall, particularly among older women, with suggestions for prevention strategies like smoking cessation and HPV vaccination to mitigate future risks.
Article Synopsis
- Lip, oral, and pharyngeal cancers represent a small portion of global cancer cases, showing lower cancer-related deaths in 2020, yet exhibit varied 5-year survival rates depending on the stage at diagnosis.
- Data was gathered from multiple cancer registries and analyzed using Joinpoint regression to detect trends in incidence and mortality related to age, gender, and location.
- Higher rates of cancer incidence and mortality were noted in regions like Melanesia and South-Central Asia, with risk factors including tobacco use, alcohol, and lifestyle diseases; increases were particularly observed in older demographic groups and females in specific countries, indicating a shift possibly linked to lifestyle changes and HPV infections.
Article Synopsis
- Melanoma is the deadliest form of skin cancer, although it shows relatively low incidence and mortality rates worldwide.
- This study aimed to analyze global trends in melanoma incidence and mortality, as well as risk factors across different demographics.
- Findings indicated an increase in melanoma cases, particularly among older adults, especially males, while mortality rates have generally decreased, suggesting a need for further research on contributing lifestyle and healthcare factors.
Article Synopsis
- Small intestinal cancer is rare but increasing globally, with an estimated incidence rate of 0.60 per 100,000 in 2020, particularly higher in North America.
- Higher incidence is linked to factors like economic status, unhealthy lifestyle habits, and metabolic disorders.
- The trend shows a rising incidence, especially among older adults (ages 50-74), highlighting the need for further research and possibly targeted interventions.
Article Synopsis
- The COVID-19 pandemic has led to lifestyle changes that may contribute to weight gain and increased obesity prevalence, which is linked to severe health problems.
- Data from a global survey of participants over 18 years old showed that younger, more educated, urban-dwelling individuals with full-time jobs were more susceptible to weight gain.
- Findings indicated that negative mental health factors, such as feelings of helplessness and unhealthy eating habits during quarantine, played a significant role in weight gain, underscoring the need for targeted mental health support moving forward.
In January 2021, the eHealth App was launched in Hong Kong by the Hong Kong government to support the Electronic Health Record Sharing System (eHRSS). A Health Management Module in the eHealth App introduced new functions to record blood pressure, blood sugar, and heart rate, and downloading and sharing records. This study aims to compare the level of glycaemic control between users of the eHealth App and non-users.
View Article and Find Full Text PDFChildhood vaccination is crucial to protect young children from harmful infectious diseases. This study aimed to investigate the recent childhood immunization rate of recommended and additional vaccinations and identify the factors affecting the vaccination uptake of young children in Hong Kong. The self-administrated questionnaires were distributed to parents of toddlers aged 2 to 5.
View Article and Find Full Text PDFIntroduction: Mesothelioma is an uncommon type of cancer which has received little attention. This study aims to evaluate the global disease burden; trends of mesothelioma by age, sex, and geographic locations; and its risk factors on the population level.
Methods: The Global Cancer Observatory, Cancer Incidence in Five Continents Plus, and Global Burden of Disease were accessed for mesothelioma incidence and its risk factors worldwide.
With the COVID-19 outbreak, emergency remote teaching - an unprepared distant mode of education became the only possible alternative for schools. The present large-scale survey with 3,672 Grade 3 and 9 students, their parents, and 863 teachers/principals was conducted in the metropolitan city of Hong Kong after half a year of school lockdown. Results showed teachers, principals, and parents were worried about students' inability to concentrate and learn without teachers' explanations.
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