Publications by authors named "Szabolcs Vigvari"

Migraine is a painful neurological condition characterized by severe pain on one or both sides of the head. It may be linked to changes in the gut microbiota, which are influenced by antibiotic use and other factors. Dysbiosis, which develops and persists as a result of earlier antibiotic therapy, changes the composition of the intestinal flora, and can lead to the development of various diseases such as metabolic disorders, obesity, hematological malignancies, neurological or behavioral disorders, and migraine.

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Purpose: Metronidazol and vancomycin were long the two best options against (formerly ) infections (CDI). Now, the cost of new drugs such as fidaxomicin directs us towards alternative treatment options, such as faecal microbiota transplant (FMT). Its effectiveness is similar to fidaxomicin.

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Dramatic changes in the epidemiology of infections have been reported from the western world in the past decade. The proportion of severe cases is significantly elevating and clinicians now have to contend with the problem of additional and more frequent episodes of recurrences including an upward trend in the mortality rate. This situation led us to investigate the possibility of the fecal microbiota transplantation (FMT).

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Article Synopsis
  • Clostridium difficile infections (CDIs) have surged in the past decade, affecting more people without traditional risk factors, resulting in increased severity and recurrence.
  • Conventional treatments like metronidazole and vancomycin remain first-line options, but new drugs like fidaxomicin show promise with lower recurrence rates.
  • A study of 886 CDI patients identified prior antibiotic use and hospitalization as major risk factors, while also suggesting prior statin use may increase CDI risk.
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Faecal microbiota transplantation (FMT) has been reported to be effective in treating relapsing of refractory Clostridium difficile infections, although some practical barriers are limiting its widespread use. In this study, our objective was to evaluate the rate of resolution of diarrhea following administration of lyophilized and resolved FMT via a nasogastric (NG) tube. We recruited 19 patients suffered from laboratory-confirmed C.

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Introduction: During the past years a dramatic change has been observed in the epidemiology of Clostridium difficile infections.

Aim: The aim of the authors was to investigate the possibility of the fecal microbiota transplantation and study differences, if any, in the success rate of the two different upper gastrointestinal tract method.

Method: 100 ml of fecal microbiota solution was instilled via a nasoduodenal tube in 15 cases and a nasogastric tube in 15 cases.

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