Publications by authors named "Syunya Ikeda"
Article Synopsis
- Glioblastoma multiforme (GBM) is a highly aggressive brain tumor that urgently needs new therapies; CAR T cell therapy has shown promise but is costly and time-intensive.
- Researchers are exploring CAR-transduced natural killer (NK) cells as an "off-the-shelf" immunotherapy alternative, which can avoid complications like graft-versus-host disease.
- Both CAR-T and CAR-NK cells targeting the B7-H3 protein demonstrated significant effectiveness in killing GBM cells in lab tests and in animal models, suggesting they could be viable treatment options for this aggressive cancer.