Publications by authors named "Synaida Maiche"

BACKGROUNDCow's milk (CM) allergy is the most common food allergy in young children. Treatment with oral immunotherapy (OIT) has shown efficacy, but high rates of adverse reactions. The aim of this study was to determine whether baked milk OIT (BMOIT) could reduce adverse reactions while still inducing desensitization, and to identify immunological correlates of successful BMOIT.

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luciferase (FLuc) has proven a valuable tool for bioluminescence imaging, but much of the light emitted from the native enzyme is absorbed by endogenous biomolecules. Thus, luciferases displaying red-shifted emission enable higher resolution during deep-tissue imaging. A robust model of how protein structure determines emission color would greatly aid the engineering of red-shifted mutants, but no consensus has been reached to date.

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Article Synopsis
  • Cow milk (CM) allergy is a common issue in young children, but current diagnostic methods are often unreliable or risky.
  • This study aimed to identify specific characteristics of T cells in CM-allergic patients that could serve as a new diagnostic marker.
  • The researchers found significant differences in the quantity and behavior of CM-specific T cells in allergic patients, leading to the development of a flow-cytometry assay that could help with diagnosing CM allergy more effectively.
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