Publications by authors named "Sylwia Wilkosz"

Article Synopsis
  • Empyema affects over 65,000 individuals annually in the U.S. and U.K., but its development process is not well understood.
  • This study used animal models and cell cultures to explore how the bacteria Streptococcus pneumoniae causes empyema, focusing on the immune response and bacterial behavior in the pleural space.
  • Findings revealed that S. pneumoniae rapidly invades the pleural area, triggers inflammatory responses, and suggests that bacteria move through mesothelial cells, highlighting potential new treatments and mechanisms for empyema.
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Purpose: This study was designed to investigate the vascular structure and angiogenic activity of human peritoneal adhesions.

Methods: Adhesions were collected from patients undergoing laparotomy (n=32). Histologic features were documented and the distribution of mature and immature vascular markers were determined by immunolocalization and quantified by image analysis.

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In humans, the greater omentum is a fatty peritoneal fold that extends from the greater curvature of the stomach to cover most abdominal organs. It performs many functions, which include acting as a reservoir of resident peritoneal inflammatory cells, a storage site for lipid, and a regulator of fluid exchange in and out of the peritoneal cavity. Most importantly, the omentum readily adheres to areas of inflammation and peritoneal damage, often leading to adhesion formation.

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