The influence of single and binary mixtures of collagen amino acids on the structure of synthetic calcium hydroxyapatite as a nanobiomaterial.

The modifications carried out as part of this study were aimed at examining the effect of the addition of collagen amino acids: glycine, proline and hydroxyproline (used separately and in binary mixtures) on the physicochemical properties of hydroxyapatite obtained in their presence . The influence of mixtures of amino acids on these properties is an important element of scientific novelty. The obtained samples were tested with the use of instrumental methods: FT-IR, TEM, EDXMA, PXRD and UV spectrophotometry.

Composites Containing Nanohydroxyapatites and a Stable TEMPO Radical: Preparation and Characterization Using Spectrophotometry, EPR and H MAS NMR.

Hydroxyapatite is the main constituent of mammalian hard tissues. Basic applications of synthetic hydroxyapatites include bone and dental implantology and drug delivery systems. The study of hydroxyapatite surface properties could give greater insight into the processes of bone mineralization and degradation.

Convenient UV-spectrophotometric determination of citrates in aqueous solutions with applications in the pharmaceutical analysis of oral electrolyte formulations.

Herein, we present a convenient method for quantitative spectrophotometric determination of citrate ions in aqueous solutions in the middle-UV range. It involves measuring the absorbance of citric acid at 209 nm under suppressed dissociation at pH < 1.0 in the presence of hydrochloric acid.

Synthesis and Antimicrobial Activity of 4-Chloro-3-Nitrophenylthiourea Derivatives Targeting Bacterial Type II Topoisomerases.

A series of novel 4-chloro-3-nitrophenylthiourea derivatives were synthesized and evaluated for their antimicrobial, antibiofilm and tuberculostatic activities. Most of compounds exhibited high antibacterial activity against both standard and hospital strains (MIC values 0.5-2 μg/mL), as compared to Ciprofloxacin.