Publications by authors named "Sylvie Nadalon"

Background: The incidence of childhood type 1 diabetes (T1D) incidence is rising in many countries, supposedly because of changing environmental factors, which are yet largely unknown. The purpose of the study was to unravel environmental markers associated with T1D.

Methods: Cases were children with T1D from the French Isis-Diab cohort.

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Objectives: To describe the features and outcomes of patients with giant cell arteritis who developed venous thrombosis.

Methods: Inception cohort study including 428 newly diagnosed patients of giant cell arteritis from 1976 to 2014. Clinical and biological data and outcomes were analysed by comparing patients with and without venous thrombosis.

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Article Synopsis
  • * Imaging tests revealed a hyperdensity in his left arytenoid cartilage, and a tracheostomy was necessary for breathing support.
  • * Further testing showed he had acromegaly, indicated by symptoms like large hands and a high IGF-1 level, linked to a pituitary adenoma, marking a unique case of acute respiratory distress tied to vocal cord immobility.
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Objectives: Giant cell arteritis (GCA) is a chronic systemic vasculitis of large and medium-sized arteries, for which long-term glucocorticoid (GC) treatment is needed. During GC withdrawal patients can suffer adrenal insufficiency. We sought to determine the time until recovery of adrenal function after long-term GC therapy, and to assess the prevalence and predictors for secondary adrenal insufficiency.

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Objective: To determine the frequency of occurrence of malignancy concurrently with temporal arteritis (TA), as well as features and outcome of the vasculitis in such cases.

Methods: In a series of 271 consecutive patients with TA (219 biopsy-proven), we retrospectively analyzed the frequency and type of malignancy concurrent with vasculitis (less than 1 year before or after), as well as the main features and outcome of TA in this setting. We also surveyed all cases published in the French-British literature.

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