Publications by Sylvie E Delanian

Publications by authors named "Sylvie E Delanian"

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Randomized, Placebo-Controlled Clinical Trial Combining Pentoxifylline-Tocopherol and Clodronate in the Treatment of Radiation-Induced Plexopathy.

Sylvie E Delanian Timothee Lenglet Thierry Maisonobe Matthieu Resche-Rigon Pierre-Francois Pradat

Int J Radiat Oncol Biol Phys

May 2020

Purpose: Radiation-induced (RI) plexopathy is a rare peripheral nerve injury after radiation therapy for cancer. No treatment has been shown to slow its progression. A pentoxifylline-vitamin E combination significantly reduced RI fibrosis, and its association with clodronate (PENTOCLO) allowed healing of osteoradionecrosis and reduction of neurologic symptoms in phase 2 trials.

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