Publications by authors named "Sylvie Dobrota"
Joint and Individual Mitochondrial DNA Variation and Cognitive Outcomes in Black and White Older Adults.
J Gerontol A Biol Sci Med Sci
September 2024
Article Synopsis
- This study investigates the role of inherited mitochondrial DNA variations in cognitive function among Black and White older adults, focusing on participants over 70 years old from two large aging studies.
- Researchers used a sequence kernel association test to analyze multiple mtDNA variants, finding significant links between specific genetic variants and cognitive test scores at baseline and their decline over time.
- The study highlights that certain mitochondrial variants in Complex I are associated with cognitive decline differently in Black and White participants, suggesting potential genetic factors influencing neurodegenerative disease risk across ethnicities.
Background: research on the association between hearing impairment and psychosocial outcomes is not only limited but also yielded mixed results.
Methods: we investigated associations between annual self-reports of hearing problems, depressive symptoms and social network strength among 5,888 adults from the Cardiovascular Health Study over a period of 9 years. Social network strength and depressive symptoms were defined using the Lubben Social Network Scale (LSNS), and the Center for Epidemiological Studies Depression Scale (CES-D).
The Burnout Dyad: A Collaborative Approach for Including Patients in a Model of Provider Burnout.
J Contin Educ Health Prof
October 2021
Both patients and providers in the United States (US) suffer from burnout, which can impact the clinical relationship and quality of care. Among providers, burnout is a state of exhaustion including heightened depersonalization; among patients, burnout can negatively affect clinical outcomes. More than half of clinical providers in the United States suffer from burnout; less is known about the magnitude and prevalence among patients.
View Article and Find Full Text PDFBackground: Ostomy surgeries involving the placement of an ostomy bag (eg, colostomy, ileostomy, urostomy, etc) have been shown to have a negative impact on health-related quality of life. To date, no studies have been conducted examining what impact, if any, wearable biosensors have on the health-related quality of life of ostomy patients.
Objective: In the present study, we plan to assess the quality of life of ostomy patients using the Ostom-i alert sensor, a portable, wearable, Bluetooth-linked biosensor that facilitates easier ostomy bag output measurements.