Open removal of a migrated Gellhorn pessary and repair of a vesicovaginal fistula.

This is a case of a 91-year-old woman presenting with urinary incontinence following insertion of a Gellhorn pessary 10 months previously. She had unfortunately missed her 6 months appointment for a change of pessary as she was admitted to hospital. Our patient was found to have had erosion of her Gellhorn shelf pessary into her urinary bladder.

Testicular Rupture or Testicular Fracture? A Case Report and Literature Review.

Testicular trauma is relatively uncommon. However, severe injuries can result in many complications and should be carefully diagnosed and managed. We present a case of testicular fracture diagnosis made by ultrasonography.

Penile Sparing Surgery for Penile Cancer: A Multicenter International Retrospective Cohort.

Purpose: We evaluated recurrence outcomes of penile sparing surgery in what is to our knowledge the largest multicenter cohort of patients to date.

Materials And Methods: We retrospectively identified patients treated with penile sparing surgery from May 1990 to July 2016 at 5 tertiary referral institutions. Treatments consisted of circumcision, wide local excision, laser therapy with or without local excision, partial or total glansectomy and glans resurfacing.

Laser ablation as monotherapy for penile squamous cell carcinoma: A multi-center cohort analysis.

Introduction: Although the trend towards penile sparing therapy is increasing for penile squamous cell carcinoma, outcomes for laser ablation therapy have not been widely reported. We assessed the clinical outcomes of penile cancer patients treated with only laser ablation.

Materials And Methods: A retrospective review was performed on 161 patients across 5 multi-center tertiary referral centers from 1985 to 2015.

Surgical management of penile carcinoma in situ: results from an international collaborative study and review of the literature.

Objectives: To evaluate recurrence after penile-sparing surgery (PSS) in the management of carcinoma in situ (CIS) of the penis in a large multicentre cohort of patients.

Patients And Methods: We identified consecutive patients from five major academic centres, treated between June 1986 and November 2014, who underwent PSS for pathologically proven penile CIS. The primary outcome was local recurrence-free survival (RFS), which was estimated using the Kaplan-Meier method.

Glansectomy as Primary Management of Penile Squamous Cell Carcinoma: An International Study Collaboration.

Objective: To analyze the recurrence and survival outcomes of glansectomy in patients with penile squamous cell carcinoma.

Materials And Methods: We performed a retrospective review of 410 patients across 5 international tertiary referral centers between 1999 and 2016. All patients had tumors involving the glans penis and underwent glansectomy as primary treatment.

Light deprivation induces depression-like behavior and suppresses neurogenesis in diurnal mongolian gerbil (Meriones unguiculatus).

Recent evidence suggests that adult neurogenesis contributes to the pathophysiology of different psychiatric disorders, including depressive disorder, anxiety disorder, and schizophrenia. Seasonal affective disorder (SAD) is a specific form of recurrent depressive disorder that can be induced by shortened light period. It is unclear yet whether neurogenesis is affected in SAD or under altered light/dark cycle.