Publications by authors named "Sylvia Vogl"

Ethnopharmacological Relevance: In Austria, like in most Western countries, knowledge about traditional medicinal plants is becoming scarce. Searching the literature concerning Austria's ethnomedicine reveals its scant scientific exploration. Aiming to substantiate the potential of medicinal plants traditionally used in Austria, 63 plant species or genera with claimed anti-inflammatory properties listed in the VOLKSMED database were assessed for their in vitro anti-inflammatory activity.

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Article Synopsis
  • Inhibition of VSMC proliferation is important for addressing cardiovascular diseases, and researchers explored an extract from the medicinal plant Peucedanum ostruthium for its potential effects on this issue.
  • The dichloromethane extract was found to significantly reduce serum-induced VSMC proliferation in a concentration-dependent manner.
  • Ostruthin, a coumarin identified in the extract, was determined to be the primary compound responsible for the antiproliferative effects.
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The rhizomes of Peucedanum ostruthium (L.) Koch (masterwort) are traditionally used in the alpine region as ingredient of liqueurs and bitters, and as a herbal drug. A sensitive and specific high-performance liquid chromatography-diode-array detection-mass spectrometry (HPLC-DAD-MS) method has been developed for the simultaneous identification and quantification of its main coumarins, oxypeucedanin hydrate, oxypeucedanin, ostruthol, imperatorin, osthole, isoimperatorin, and ostruthin.

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