[Nerve distribution and density in the canine hip joint capsule. Comparison of healthy and dysplastic hip joints].

Objective: The hip-joint capsule is exposed to increased tension forces during canine hip dysplasia, resulting in inflammation of the capsular tissue. It has been postulated that inflammation is associated with an increased nerve-distribution density. Therefore, it could be supposed that the nerve-distribution density in the hip-joint capsule is higher in dogs with dysplastic hip compared to healthy dogs.

Magnetic resonance-guided angioplasty with delivery of contrast-media doped solutions to the vessel wall: an experimental study in swine.

Objectives: To assess the feasibility of magnetic resonance (MR)-guided delivery of a solution containing contrast-medium and immediate online monitoring of its distribution to the vessel wall during MR-guided angioplasty in peripheral arteries.

Materials And Methods: In 3 pigs, the feasibility of MR-guided atraumatic delivery of a solution containing contrast-medium and tissue dye (0.05 mmol/mL Gd-DTPA, 3% Evans blue dye) into the vessel wall of the iliac arteries was tested using a permeable balloon catheter (8 mm).

Long-term retrieval of modified Günther Tulip vena cava Filters: an animal study.

We modified the Günther Tulip Filter to allow long-term retrieval and tested this modified filter design in an animal experiment. Fourteen modified Günther Tulip Filters (Celect filter) were inserted percutaneously into the inferior venae cavae of 7 domestic adult sheep (2 filters per animal). Before removal, 3 months after filter placement, cavography was performed and the filters were removed.

Late-phase MSCT in the different stages of myocardial infarction: animal experiments.

The purpose of this study was to intraindividually evaluate myocardial late enhancement on multislice spiral computed tomography (MSCT) for the assessment of the different stages of myocardial infarction (MI) in comparison with magnetic resonance (MR) imaging. Reperfused MI was successfully induced in seven pigs. Delayed enhancement MR imaging and late-phase MSCT were performed on day 0 as well as 7, 28 and 90 days after the procedure.

Molecular magnetic resonance imaging of atrial clots in a swine model.

Background: The detection and differentiation of intracardiac masses is still challenging and may include neoplasms and thrombi. The aim of this study was the investigation of a targeted, fibrin-specific contrast agent (EP-2104R) for molecular targeted magnetic resonance imaging (MRI) of left atrial clots.

Methods And Results: Chronic human thrombi were surgically implanted in the left atrial appendage of 5 swine.

MR-guided percutaneous intramyocardial injection with an MR-compatible catheter: feasibility and changes in T1 values after injection of extracellular contrast medium in pigs.

Purpose: To assess the feasibility of percutaneous magnetic resonance (MR)-guided intramyocardial injection of gadodiamide by using real-time imaging and to quantify T1 values and the size of the enhanced region for different concentrations of contrast agent for 30 minutes after injection.

Materials And Methods: Animal care committee approval was obtained. A catheter with a needle tip was advanced into the left ventricle in seven pigs by using real-time imaging with radial steady-state free precession.

Minimally invasive close-chest method for creating reperfused or occlusive myocardial infarction in swine.

Rationale And Objectives: We sought to evaluate a closed-chest model for reperfused and occlusive myocardial infarction (MI) in pigs and to report experiences and pitfalls.

Material And Methods: In 44 pigs, a balloon catheter was advanced into the left descending coronary artery (LAD) under fluoroscopic guidance. The balloon was inflated and occlusion of the vessel angiographically confirmed while ECG was continuously monitored.

Use of a nonmetallic guide wire for magnetic resonance-guided coronary artery catheterization.

Rationale And Objectives: Metallic guide wires can be subject to substantial heating when used in the magnetic resonance (MR) environment. Therefore, animal experiments were performed to test the feasibility of a non-metallic and MR-safe guide wire with passive markers for catheterization of coronary arteries under MR guidance.

Materials And Methods: Self-made guide wires consisting of a resin-microparticle compound covered by polytetrafluoroethylene were used to catheterize both coronary arteries of swine together with a non-braided catheter.

[Cauda equina compression syndrome (CECS): retrospective study of surgical treatment with partial dorsal laminectomy in 86 dogs with lumbosacral stenosis].

We report our results of partial lumbosacral laminectomy for treatment of canine Cauda equina Compression Syndrome due to a lumbosacral stenosis. Opposite to conventional techniques of dorsal laminectomy, only widening of the Spatium interarcuale is performed. This is achieved by exstirpation of the Lig.

New metallic MR stents for artifact-free coronary MR angiography: feasibility study in a swine model.

Rationale And Objectives: The objective of this study was to investigate the potential for artifact-free coronary magnetic resonance angiography (cMRA) in the presence of dedicated metallic MR stents in vitro and in a swine model.

Methods: All investigations were performed at 1.5 T, applying a standard cMRA gradient echo sequence with a T2 preparation pulse.

Diagnosis and treatment of arthrosis of cervical articular facet joints in Scottish Deerhounds: 9 cases (1998-2002).

Objective: To determine diagnostic features and efficacy of treatment of arthrosis of the cervical articular facet joints between C2 and C3 in Scottish Deerhounds.

Design: Retrospective study.

Animals: 9 client-owned dogs.

[Hypofractionated radiation therapy for the treatment of malignant melanoma and squamous cell carcinoma in dogs and cats].

This study describes the experience with hypofractionated radiation therapy of squamous cell carcinoma and melanoma in dogs and cats. A total dose of 32-48 Gray (Gy) was delivered once a week in 8 Gy fractions. 34 animals in which a complete surgical excision was impossible were treated.

Effect of intraperitoneal antiadhesive fluids in a rat peritonitis model.

Hypothesis: Phospholipids and icodextrin reduce peritoneal adhesions resulting from general peritonitis without promoting abscess formation.

Design: Evaluation of adhesion reduction fluids in a randomized animal study using a standardized peritonitis model.

Setting: Experimental animal model in a university laboratory.

Simultaneous real-time visualization of the catheter tip and vascular anatomy for MR-guided PTA of iliac arteries in an animal model.

Purpose: To examine the feasibility of simultaneous MR real-time active tip tracking and near real-time depiction of the vascular anatomy for percutaneous angioplasty of iliac arteries under MR guidance.

Materials And Methods: Nine surgically created stenoses of external iliac arteries in pigs were dilated with MR-compatible balloon catheters (Cordis, Roden, The Netherlands). These catheters were equipped with a microcoil for active tracking of the catheter tip with an in-plane update rate of 10 positions per second.

[10 years experience with denervation of the hip joint capsule for treatment of canine hip joint dysplasia and arthrosis].

Denervation of the canine hip joint capsule is described as a surgical therapy method in the treatment of canine hip joint dysplasia and arthrosis. The goal of this operation is a removal of the pain immediately and a reactivation of the dynamic active component of the hip joint in moving the body forward. Simple removal of the periosteum of the craniolateral acetabulum edge destroys the rami articulares of the cranial glutaeal nerve and the rami articulares dorsalis of the sciatic nerve.