Publications by authors named "Sylvia Hsu"
A Caucasian woman in her twenties having asymptomatic papules on the hands for the past 6 months was referred by rheumatology for a skin biopsy. The patient had presented to rheumatologist for arthralgia. On physical examination, multiple, dull red, 2-5-mm papules were observed on her dorsal fingers, with most in the periungual regions.
View Article and Find Full Text PDFMonoclonal gammopathy of undetermined significance (MGUS) is a pre-malignant condition of multiple myeloma (MM). Evidence suggested old age, black race, male gender, and obesity as risk factors for MGUS development; however, whether they are associated with an increased risk of progression to MM among patients with MGUS is unclear. A systematic search of PUBMED and EMBASE for cohort studies investigating the association between age/race/gender/obesity and progression to MM.
View Article and Find Full Text PDFA 79-year-old woman with psoriasis presented to the emergency department with new-onset eruptions on the trunk, extremities, and oral mucosa for 8-9 days. For psoriasis, she had been taking 15 mg of methotrexate weekly for over 18 years, and had discontinued folic acid a few months prior to this.
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- - A 55-year-old woman developed alopecia areata (AA) after a year of treatment with upadacitinib for her atopic dermatitis.
- - This case is significant as it suggests a potential link between upadacitinib and the onset of AA, a connection not previously documented.
- - The report emphasizes the usual timeline for drug-induced hair loss and prompts further investigation into the possibility of upadacitinib causing such side effects.
Article Synopsis
- A 34-year-old African-American woman with a history of HIV and hypertension visited the clinic due to recurring blisters on her face, specifically her nose and cheeks, for the past 8 months.
- The blisters appear about once a month, can be itchy, but resolve on their own without intervention.
- At her appointment, the only noticeable issue was post-inflammatory hyperpigmentation on her nose, and she had photos on her phone to illustrate the blisters' appearance.
A 40-year-old African-American man was referred to our dermatology clinic for management of his long-standing thyroid dermopathy. The patient was diagnosed with hyperthyroidism at the age of 20, and was treated with radioactive iodine I-131 but subsequently lost to follow-up. He had not consulted physicians again until the age of 30.
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- Systemic immunomodulatory agents are used to treat moderate-to-severe plaque psoriasis and psoriatic arthritis, but their use before surgery may raise the risk of infections and complications.
- The study aimed to assess the risk of surgical site infections (SSI) in patients with autoimmune diseases who are on various immunomodulatory drugs and undergoing surgery.
- Findings suggest that for low-risk surgeries, many immunomodulatory treatments, such as TNF-α inhibitors and methotrexate, can be safely continued, while for more complex surgeries, a careful evaluation is recommended before continuing their use.
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- Pigmented purpuric lichenoid dermatitis (PPLD) is a rare skin condition characterized by lichenoid papules and patches, primarily occurring on the lower legs.
- A case study discusses a 47-year-old man who exhibited 1-3mm discrete papules but lacked larger patches, which is atypical for PPLD.
- It is important for healthcare providers to consider a diagnosis of PPLD in patients with bilateral symmetric discrete papules on their legs.
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- Pemphigoid gestationis (PG) is a rare autoimmune skin condition that occurs during pregnancy or shortly after childbirth.
- There may be a connection between PG and Graves' disease, but the evidence is inconsistent, with previous studies often finding that Graves' disease was diagnosed before PG.
- More research is needed, especially long-term studies, to understand the lifetime risk of developing Graves' disease in women who have experienced PG.
Article Synopsis
- A 16-year-old African American girl presented with white spicules on her face for two years, with no symptoms like itching or pain.
- Physical exams revealed 1-2 mm white to yellow filamentous spicules, and histopathology indicated the presence of cornified cells and calcification related to sebaceous filaments.
- Treatment aims to reduce sebaceous gland size, improving skin appearance, and the patient responded well to topical tretinoin, highlighting the importance of recognizing this rare condition in dermatology.
Article Synopsis
- - Erythrasma is a frequent skin infection found in adults but is rarely reported in children.
- - The case discussed involves a four-year-old child with interdigital pedal erythrasma.
- - The child exhibited symptoms of itchy, scaly skin with signs of maceration.
Flush reactions can be incited by various factors including inherent mutation, drugs, and diseases. A medication that is commonly used in dermatology but less associated with alcohol-induced facial flushing is topical tacrolimus. We present the case of a 44-year-old man experiencing this phenomenon on a distant, non-application site and a review of cases published in the literature.
View Article and Find Full Text PDFTreating an acneiform eruption requires the discovery of its etiology. Often, the removal of the offending agent can lead to the resolution of the eruption, resulting in an excellent prognosis. Herein, we present a rare case of a vitamin B12-induced acneiform eruption occurring in a 68-year-old female due to an over-the-counter supplement.
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