Publications by authors named "Sylvia Ai"
Objective: The objective of this study is to determine if there are differences in outcome for patients diagnosed with multiple myeloma in a rural setting compared to a metropolitan setting and which factors influence these outcomes.
Design: Retrospective cohort study.
Setting: Illawarra Shoalhaven Local Health District.
Sequential high-dose methotrexate and cytarabine administration improves outcomes in real-world patients with primary central nervous system lymphoma: A report from the Australasian Lymphoma Alliance.
EJHaem
August 2024
Article Synopsis
- Researchers examined treatment options for primary CNS lymphoma in adult patients, focusing on five chemotherapy regimens that include high-dose methotrexate (HD-MTX).
- Out of 204 patients in the study, a significant majority (93%) received various combinations of HD-MTX and other drugs, with the MPV/Ara-C regimen showing the best results in progression-free and overall survival rates.
- The study concluded that using tailored treatment strategies can boost recovery rates, especially for older patients not suited for more aggressive therapies.
Background: Antenatal screening is vital to identifying couples at risk of having children with a clinically significant haemoglobinopathy. In Australia, immigration is increasing carrier incidence.
Methods: A retrospective analysis was performed of full blood count, high-performance liquid chromatography and haemoglobin electrophoresis of women and their partners who underwent antenatal haemoglobinopathy screening over three years at a major NSW laboratory.