Publications by authors named "Sylvette Wiener-Vacher"

Importance: Children with profound hearing loss (HL) and vestibular impairment have worse cochlear implant outcomes compared with those without vestibular impairment. However, the decision for cochlear implantation is rarely based on vestibular function assessment as a complement to audiologic testing.

Objectives: To identify the prevalence of vestibular impairment according to HL origin and to assess the association between vestibular impairment and delayed posturomotor development in children with profound HL.

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Objective: To compare the amplitude ratio and P-wave latency of cervical vestibular evoked myogenic potentials (c-VEMPs) for bone conduction (BC) and air conduction (AC) stimulation in children with otitis media with effusion (OME).

Material And Methods: This is an observational study of a cohort of 27 children and 46 ears with OME. The c-VEMP amplitude ratio and P-wave latency were compared between BC and AC in children with OME and healthy age-matched children.

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Objectives: To characterize cervical vestibular evoked myogenic potentials (c-VEMPs) in bone conduction (BC) and air conduction (AC) in healthy children, to compare the responses to adults and to provide normative values according to age and sex.

Design: Observational study in a large cohort of healthy children ( = 118) and adults ( = 41). The c-VEMPs were normalized with the individual EMG traces, the amplitude ratios were modeled with the Royston-Wright method.

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Article Synopsis
  • The study aimed to understand how congenital cytomegalovirus infection affects cochlear (hearing) and vestibular (balance) functions in children by conducting a retrospective evaluation of 130 children diagnosed with the infection.
  • Results showed that 64% had inner ear impairments, with vestibular dysfunction being more common than cochlear issues (ρ = 0.003), highlighting the critical need to assess both functions.
  • Among the children evaluated, nearly half exhibited hearing impairments, with profound losses often being bilateral; 97% of those with a history of normal hearing screening developed vestibular disorders, stressing the importance of ongoing evaluation beyond initial testing.
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Article Synopsis
  • - The study aimed to identify factors that predict hearing and vestibular impairment in children born with congenital cytomegalovirus (cCMV), analyzing clinical and imaging data from pregnancy and birth for 130 subjects between March 2014 and March 2020.
  • - Results showed that 64% of the children had inner ear impairments, but factors like sex, maternal infection type, and neonatal signs didn't significantly correlate with these impairments.
  • - The key findings highlight that antenatal imaging lesions and CMV infection during the first trimester are strong predictors of inner ear problems, while infections in the second and third trimesters were less likely to lead to such issues.
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Congenital cytomegalovirus (CMV) infection leads to olfactory bulb lesions in the fetus, yet little is known about its impact on olfaction after birth. Here, we have assessed in a prospective study conducted on children in two French hospitals from 2016 to 2019, infection severity and olfactory performance after congenital CMV infection. Children with congenital CMV infection aged 3 to 10 years and healthy controls (CTL) matched for age and sex to CMV children symptomatic at birth (sCMV) were enrolled.

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This paper describes the diagnostic criteria for "Vestibular Migraine of Childhood", "probable Vestibular Migraine of Childhood" and "Recurrent Vertigo of Childhood" as put forth by the Committee for the Classification of Vestibular Disorders of the Bárány Society (ICVD) and the Migraine Classification subgroup of the International Headache Society. Migraine plays an important role in some subgroups of children with recurrent vertigo. In this classification paper a spectrum of three disorders is described in which the migraine component varies from definite to possibly absent.

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Background: Verticality, or more precisely the ability to perceive spatial orientation with regard to gravity, is based on the integration of visual, vestibular and somesthetic information.

Objective: The purpose of the present study was to compare the subjective visual vertical (SVV) in patients with Usher (type I and type II) with visual or vestibular impairment, and in healthy participants, in order to explore the importance of the visual and vestibular functions on the vertical’s perception.

Methods: We evaluated the SVV using a wall housing which projects on the opposite wall a red-light line of about 2 meters, obtained by laser cannon.

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Article Synopsis
  • Vestibular assessments are crucial for early identifying balance issues in children, with cVEMPs and oVEMPs showing effectiveness in evaluating otolith function.
  • The study involved 33 healthy children aged 5 to 12, using specific auditory stimuli and equipment to measure their vestibular responses.
  • Results provided normative data for cVEMPs and oVEMPs, which can help health professionals assess balance and vestibular function in Malaysian children.
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A decrease in visual perception with age was observed due to a decline in neurocognitive and visual functions. Previous studies showed that aging affects visual processes and contextual perceptual phenomena. The aim of our study was to explore the effect of age as well as the effect of Age-Related Macular Degeneration (AMD) on the visual searching task.

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This study investigated postural performances and vestibular impairment in Usher patients. The three groups studied were: 11 patients with Usher type I (with visual and vestibular impairment), 14 patients with Usher type II (with only visual impairment), and 14 healthy control subjects. Postural stability was measured with a Framiral Multitest Equilibre platform with three visual conditions: eyes open (EO), eyes closed (EC), and vision disturbed by optokinetic stimulation (OPT), and two different postural conditions: stable or unstable platform.

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Objective: In children screened for dizziness with vergence disorders, we tested short and long term efficacy of orthoptic vergence training (OVT) and instructions to reduce screen usage.

Methods: Prospective study: Of the 179 children referred for vertigo or dizziness (over 3 years) with ophthalmological disorder as the only problem after complete oto-neuro-vestibular testing, 69 presented vergence insufficiency, and 49 accepted to participate in this study. 109 healthy children served as controls.

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Background: The aim of this multicenter study is to investigate the effect of chronological age and gender in postural control.

Methods: To approach an ecological model, we used a multicenter posturography assessment. We analyzed postural control with surface, mean velocity of center of pressure [CoP] and temporal analysis, with Postural Instability Index [PII] being a more sensitive parameter in postural evaluation.

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The purpose of this study was to report the prevalence of vestibular impairment (VI) in children (  = 2,528) referred for complete vestibular testing because of balance disorders (BD) or hearing loss (H). A VI was shown in 51.5% of the children tested (1,304/2,528).

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Acute vestibular syndrome (AVS) is characterized by severe posturo-locomotor and vestibulo-oculomotor impairment and accompanies several types of peripheral vestibulopathies (PVP). We know very little about its etiology, how its various symptoms are expressed and how it evolves with age. Robust repair capabilities of primary vestibular synapses have recently been shown to restore behavioral functionality.

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The video head impulse test (VHIT) is widely used to identify semicircular canal function impairments in adults. But classical VHIT testing systems attach goggles tightly to the head, which is not tolerated by infants. Remote video detection of head and eye movements resolves this issue and, here, we report VHIT protocols and normative values for children.

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Aim: The aim of this study was to understand the role played by visual information on the development of verticality and postural stability in healthy children.

Methods: The study comprised 66 healthy children from 4.0 to 15.

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While the overall development of saccades in children has recently gained increasing interest, the precise characteristics of vertical saccades remain understudied. The few adult studies existing showed up/down anisotropies on various parameters. This study focuses on the development of vertical saccades and their interaction with vergence movements, according to the mode of initiation of the saccades (automatic and controlled).

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CHARGE syndrome (MIM#214800) (Coloboma, Heart defect, Atresia of choanae, Retarded growth and development, Genital hypoplasia, Ear abnormalities/deafness) is caused by heterozygous mutation of CHD7 transmitted in an autosomal dominant manner. In this report, we describe a patient with bilateral hearing impairment, unusually-shaped ears, no intellectual disability and a patent ductus arteriosus. Further investigation showed abnormal semicircular canals and the presence of olfactory bulbs.

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Background: Congenital cytomegalovirus (CMV) infection is the leading infectious cause of neurologic disabilities and sensorineural hearing loss in children. Sensorineural hearing loss prevalence in CMV suggests a viral tropism for the inner ear. Vestibular disorders induced by CMV infection are underestimated.

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Eye movements affect postural stability in children. The present study focuses on the effect of different types of eye movements on postural stability in healthy children. Both eye movements and postural stability have been recorded in 51 healthy children from 6.

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Purpose: We compared postural stability and subjective visual vertical performance in a group of very preterm-born children aged 3-4 years and in a group of age-matched full-term children.

Materials And Methods: A platform (from TechnoConcept) was used to measure postural control in children. Perception of subjective visual vertical was also recorded with posture while the child had to adjust the vertical in the dark or with visual perturbation.

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Objectives: To analyze vestibular function Q2 (VF) after cochlear implantation (CI) in children.

Methods: Retrospective cohort study at a tertiary pediatric referral center. 43 children that had vestibular testing (VT) after unilateral cochlear implantation, from 2001 to 2010, were included.

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The aim of this study was to explore further the development of postural control in healthy children. The novelty of this study was to resort to both spatial and temporal analysis of the center of pressure (CoP). Forty-six healthy children from 4 to 16 years old (mean age: 9.

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Objective: To examine the effect of proprioceptive information during postural control in strabismic children.

Methods: Postural stability was recorded with a platform (Techno Concept®) in 12 strabismic children aged from 4.9 to 10 years and data were compared to that of 12 control age-matched children.

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