Publications by authors named "Sylvain Leroy"

Background: Catatonia is a psychomotor syndrome frequently observed in disorders with neurodevelopmental impairments, including psychiatric disorders such as schizophrenia. The orbitofrontal cortex (OFC) has been repeatedly associated with catatonia. It presents with an important interindividual morphological variability, with three distinct H-shaped sulcal patterns, types I, II, and III, based on the continuity of the medial and lateral orbital sulci.

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Article Synopsis
  • Esketamine has been proven effective for treatment-resistant depression (TRD), but its high cost and limited knowledge on treatment duration highlight the need for better outcome predictions.* -
  • A study with TRD patients receiving esketamine identified two response trajectories—responders and non-responders—while showing that initial depression scores can predict future treatment success with 80% accuracy.* -
  • Although the findings are promising, the study's observational nature and lack of a placebo group mean more controlled experiments are needed to validate these predictions and improve treatment decisions.*
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During pregnancy, the opening of the cervix can be measured by perineal echotomography. Among 200 per-gravidic clinical echotomographies, 23 cervical incompetences were recognized. A "funnel-shaped" cervix is a cervix with an internal os larger than the external os; thus no clinical sign may be apparent and only a supra-vaginal Shirodkar's operation should be done.

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Perineal echotomography is a method for measuring the dilatation of the cervix and is a good measure of the cervix during pregnancy. It permits visualization of the bag of waters, the presentation of the fetus and of the low-lying placenta.

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