A multicenter cohort study to investigate the factors associated with functional autonomy change in patients with cognitive complaint or neurocognitive disorders: the MEMORA study protocol.

Background: The identification of factors associated with functional impairment, in particular those which are potentially modifiable, may help to delay the advanced stages of functional dependence in patients with neurocognitive disorders such as Alzheimer's disease and related disorders. The objectives of the MEMORA cohort are to investigate the factors associated, first with functional autonomy change over time, and secondarily with the cognitive performance and behavioral disorders changes over time.

Methods: The MEMORA study is a multicenter prospective cohort study carried out throughout the patient's care pathway, in Memory centers of Lyon (France).

[Geriatric assessment: principles and feasibility in oncology].

Geriatric assessment is a method aimed to describe elderly individual's health status. Effectiveness has been demonstrated in different domains. The ultimate outcome of Comprehensive Geriatric Assessment is the development of a coordinated care plan in which geriatric interventions focus on the particular problems of each patient.

[The handling of anti-cancer drugs in elderly patients].

Unlabelled: The management of elderly patients with cancer is not established. The use of antineoplastic agents (particularly of chemotherapy) raises a lot of questions. Efficiency and toxicity.

[Current views in geriatric oncology].

Geriatric oncology represents a novel specialty which can be defined as specific older cancer patients management. It includes a validated geriatric procedure, the comprehensive geriatric assessment, which is the best way of approaching the complex interacting medical problems of frail older patients. Geriatric assessment of elderly cancer patients is actually a subject for discussion among geriatric oncology community.