Publications by authors named "Sylla P"

Article Synopsis
  • - Robotic surgery procedures are on the rise globally, and numerous innovative robotic platforms are being developed for imminent approval in the US within the next couple of years.
  • - A review by the SAGES Robotic Platforms Working Group highlighted twenty robotic systems in various stages of development, detailing their components, features, regulatory status, and target markets.
  • - The introduction of these new robotic platforms could enhance minimally invasive surgery, foster innovation, and potentially lower costs for patients, indicating strong future growth in robotic surgical technology.
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Background: Small bowel obstructions (SBOs) are a common complication following staged IPAA. Our goal was to compare early post-operative SBO outcomes between different staged ileal pouch-anal anastomosis (IPAA) and to further analyze the type of procedures required in patients who needed operative management of SBO.

Methods: In this retrospective cohort study, we selected all patients who presented to our tertiary care center between 2008 and 2017, with ulcerative colitis or IBD-Unspecified colitis and who underwent a primary total proctocolectomy with IPAA for medically refractory disease or dysplasia (n = 623).

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Article Synopsis
  • - The Fundamentals of Leadership Development (FLD) Curriculum aims to enhance diversity, equity, and inclusion (DEI) within leadership skills by assessing short-term impacts through pilot courses and different delivery methods.
  • - A total of 79 SAGES Committee members registered, with a completion rate of 69.7%. Most participants self-identified as underrepresented in medicine, and course engagement was notably higher in the intensive 2-day format compared to the 4-week longitudinal format.
  • - Participants reported increased confidence after completing the modules, but the longitudinal course experienced a decline in weekly participation, showing varying levels of engagement across different delivery methods.
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Background: Colorectal anastomotic leakage remains one of the most frequent and dreaded postoperative complications following colorectal resection. However, limited research has been conducted on the impact of this complication on quality of life of patients undergoing colorectal cancer surgery.

Objective: The aim of this systematic review was to identify, appraise and synthesize the available evidence regarding quality of life in patients with anastomotic leakage following oncological colorectal resections in order to inform clinical decision-making.

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Article Synopsis
  • Surgical care in the operating room creates a lot of greenhouse gas emissions, making up a third of healthcare's total emissions.
  • A big study looked at many articles about how gastrointestinal surgery affects the environment to find ways to make it more sustainable.
  • The results showed that using less anesthetic gases and reducing surgical waste can significantly help lessen the impact on the environment, and having special teams to promote these changes is a good idea.
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Article Synopsis
  • Surgeons around the world are interested in making surgery more eco-friendly, so a group was formed to learn more about their thoughts on this topic.
  • They sent out a survey to understand how surgeons feel about being sustainable, how much they know about the carbon footprint of their surgeries, and what changes they are willing to make.
  • The results showed that most surgeons want to help the environment but don’t know much about how their practices affect it; they prefer learning through online resources.
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Background: Large Language Models (LLMs) provide clinical guidance with inconsistent accuracy due to limitations with their training dataset. LLMs are "teachable" through customization. We compared the ability of the generic ChatGPT-4 model and a customized version of ChatGPT-4 to provide recommendations for the surgical management of gastroesophageal reflux disease (GERD) to both surgeons and patients.

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Purpose: Concerns exist regarding the potential for transanal total mesorectal excision (TaTME) to yield poorer functional outcomes compared to laparoscopic TME (LaTME). The aim of this study is to assess the functional outcomes following taTME and LaTME, focusing on bowel, anorectal, and urogenital disorders and their impact on the patient's QoL.

Methods: A systematic review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and A Measurement Tool to Assess systematic Reviews (AMSTAR) guidelines.

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Background: Although attempts have been made in the past to establish consensus regarding the definitions and grading of the severity of colorectal anastomotic leakage, widespread adoption has remained limited.

Objective: A systematic review of the literature was conducted to examine the various elements used to report and define anastomotic leakage in colorectal cancer resections.

Data Sources: A systematic review was conducted using the PubMed, Embase, and Cochrane Library Database.

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Article Synopsis
  • The healthcare system has a big impact on the environment, especially operating rooms, which contribute a lot to carbon emissions.
  • Major organizations and governments are working together to make healthcare more sustainable and reduce its carbon footprint.
  • A new group called the Sustainability in Surgical Practice task force was formed to promote better practices and encourage actions that help both surgery and the environment.
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Background: Diversity, equity, and inclusion have been an intentional focus for SAGES well before the COVID-19 pandemic and the coincident societal recognition of social injustices and racism. Longstanding inequities within our society, healthcare, and the surgery profession have come to light in the aftermath of events that rose to attention around the time of Covid. In so doing, they have brought into focus disparities, injustices, and inequalities that have long been present in the field of surgery, selectively affecting the most vulnerable.

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Article Synopsis
  • The study aims to assess the impact of transanal total mesorectal excision (taTME) on fecal incontinence and various functional outcomes (defecatory, urinary, and sexual) in patients with rectal cancer.
  • It was found that while initial outcomes post-surgery showed a decline in fecal continence and defecatory function, patient outcomes improved significantly by 12 months after ileostomy closure, though they did not fully recover to preoperative levels.
  • Urinary function remained stable throughout the study, but both female and male sexual functions declined without signs of recovery in the follow-up period.
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Aim: The benefits and short-term outcomes of transanal total mesorectal excision (taTME) for rectal cancer have been demonstrated previously, but questions remain regarding the oncologic outcomes following this challenging procedure. The purpose of this study was to analyze the oncologic outcomes following taTME at high-volume centers in the USA.

Methods: This was a multicenter, retrospective observational study of 8 tertiary care centers.

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Aim: Although proximal faecal diversion is standard of care to protect patients with high-risk colorectal anastomoses against septic complications of anastomotic leakage, it is associated with significant morbidity. The Colovac device (CD) is an intraluminal bypass device intended to avoid stoma creation in patients undergoing low anterior resection. A preliminary study (SAFE-1) completed in three European centres demonstrated 100% protection of colorectal anastomoses in 15 patients, as evidenced by the absence of faeces below the CD.

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Background: When pregnant patients present with nonobstetric pathology, the physicians caring for them may be uncertain about the optimal management strategy. The aim of this guideline is to develop evidence-based recommendations for pregnant patients presenting with common surgical pathologies including appendicitis, biliary disease, and inflammatory bowel disease (IBD).

Methods: The Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) Guidelines Committee convened a working group to address these issues.

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Background: The Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) has long recognized and championed increasing diversity within the surgical workplace. SAGES initiated the Fundamentals of Leadership Development (FLD) Curriculum to address these needs and to provide surgeon leaders with the necessary tools and skills to promote diversity, equity, and inclusion (DEI) in surgical practice. In 2019, the American College of Surgeons issued a request for anti-racism initiatives which lead to the partnering of the two societies.

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Article Synopsis
  • A study evaluated the effectiveness of various large language model (LLM)-linked chatbots in giving recommendations for the surgical treatment of gastroesophageal reflux disease (GERD), based on guidelines from the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES).
  • Different chatbots like ChatGPT-4, Copilot, Google Bard, and Perplexity AI were tested on specific patient cases, measuring how accurately their recommendations matched the SAGES guidelines.
  • Results showed varying accuracy rates, with Google Bard performing best for surgeons (85.7%) and ChatGPT-4 being the most accurate for patients (60%), indicating the potential and limitations of LLMs in clinical settings, and highlighting the need for better training with
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Article Synopsis
  • The SAGES Guidelines Committee is updating its procedures to create clinical practice guidelines that address health disparities among different populations.
  • The updates aim to integrate health equity issues throughout the guideline development process, promoting better patient counseling and research recommendations.
  • Ultimately, the goal is to prevent the exacerbation of health disparities while ensuring that guidelines are more inclusive and effective for all communities.
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Assembled genome sequences are being generated at an exponential rate. Here we present FCS-GX, part of NCBI's Foreign Contamination Screen (FCS) tool suite, optimized to identify and remove contaminant sequences in new genomes. FCS-GX screens most genomes in 0.

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Article Synopsis
  • - The study aimed to adapt and validate a tool for assessing ultra-processed food (UPF) consumption in Senegal, based on the Nova food classification system, which links UPF to obesity and chronic diseases.
  • - Using expert input and market data, the researchers modified the screener and tested it with a sample of 301 adults in Dakar, comparing results against a 24-hour dietary recall.
  • - Findings indicated a strong positive correlation between the Nova-UPF score and UPF dietary share, confirming the adapted screener as a reliable method for estimating UPF consumption in the Senegalese population.
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Purpose: To assess the role of pretreatment multiparametric (mp)MRI-based radiomic features in predicting pathologic complete response (pCR) of locally advanced rectal cancer (LARC) to neoadjuvant chemoradiation therapy (nCRT).

Methods: This was a retrospective dual-center study including 98 patients (M/F 77/21, mean age 60 years) with LARC who underwent pretreatment mpMRI followed by nCRT and total mesorectal excision or watch and wait. Fifty-eight patients from institution 1 constituted the training set and 40 from institution 2 the validation set.

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Background: Variation exists in practice pertaining to bowel preparation before minimally invasive colorectal surgery. A survey of EAES members prioritized this topic to be addressed by a clinical practice guideline.

Objective: The aim of the study was to develop evidence-informed clinical practice recommendations on the use of bowel preparation before minimally invasive colorectal surgery, through evidence synthesis and a structured evidence-to-decision framework by an interdisciplinary panel of stakeholders.

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Background: Micronutrient deficiencies may occur after restorative proctocolectomy (RPC) with ileal pouch-anal anastomosis (IPAA) in patients with ulcerative colitis (UC), largely due to malabsorption and/or pouch inflammation.

Objectives: The objective of this study was to report the frequency of iron deficiency in patients with UC who underwent RPC with IPAA and identify associated risk factors.

Methods: We conducted a retrospective chart review of patients with UC or IBD-unclassified who underwent RPC with IPAA at Mount Sinai Hospital between 2008 and 2017.

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