Integrated bioinformatics approach to unwind key genes and pathways involved in colorectal cancer.

Background: Colorectal cancer (CRC) is the fifth leading cause of death in India. Until now, the exact pathogenesis concerning CRC signaling pathways is largely unknown; however, the diseased condition is believed to deteriorate with lifestyle, aging, and inherited genetic disorders. Hence, the identification of hub genes and therapeutic targets is of great importance for disease monitoring.

Data on GC-MS analysis, in vitro anti-oxidant and anti-microbial activity of the and leaf extracts.

The article reports data on chemical profiling by gas chromatography-mass spectrometry (GC-MS) of aqueous and methanolic leaf extracts of Madagascar periwinkle () and drumstick tree () and on their antioxidant and antibacterial effects against three clinical human pathogens. In total 105 compounds were tentatively identified; in which 65 in and 40 in compounds. A large number of peaks with good area percentage was found in methanolic extract of with core chemical constituents such as -squalene, n-hexadecanoic acid, Eicosyl acetate, stearin, 1H-Benz(G)indole-3-carboxylic acid.