Publications by authors named "Syed Zia Ul Hasnain"
The significance of this study lies in its exploration of bioactive plant extracts as a promising avenue for combating oral bacterial pathogens, offering a novel strategy for biofilm eradication that could potentially revolutionize oral health treatments. Oral bacterial infections are common in diabetic patients; however, due to the development of resistance, treatment options are limited. Considering the excellent antimicrobial properties of phenolic compounds, we investigated them against isolated oral pathogens using and models.
View Article and Find Full Text PDFOral bacterial biofilms are the main reason for the progression of resistance to antimicrobial agents that may lead to severe conditions, including periodontitis and gingivitis. Essential oil-based nanocomposites can be a promising treatment option. We investigated cardamom, cinnamon, and clove essential oils for their potential in the treatment of oral bacterial infections using and computational tools.
View Article and Find Full Text PDFMango peel extracts and mangiferin chromatographic Fourier-transform infrared correlation with antioxidant, antidiabetic, and advanced glycation end product inhibitory potentials using in silico modeling and in vitro assays.
Biomed Chromatogr
September 2024
Article Synopsis
- Mangifera indica (mango) peels are often discarded but contain important bioactive compounds, including flavonoids and xanthonoids, with potential health benefits, particularly for diabetes management.
- The methanolic extract of the Langra variety of mango showed lower phenol concentrations compared to its chloroform and ethyl acetate fractions, while the Sindhri variety exhibited similar patterns with higher concentrations in the other extracts.
- Both varieties demonstrated significant antidiabetic properties, particularly through α-glucosidase inhibition and preventing the formation of advanced glycation end products, indicating that mango peel waste could be valuable in diabetes treatment.
Background: Oral bacterial infections are difficult to treat due to emergence of resistance against antibiotic therapy. Essential oils are considered emerging alternate therapy against bacterial infections and biofilms. We investigated Citrus bergemia flower essential oil against oral pathogens.
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