Publications by authors named "Syed Zeeshan Haider"

Article Synopsis
  • - This study explored how enzymes from the marine bacterium Bacillus ligniniphilus L1 can break down natural and synthetic estrogen compounds, using both computational modeling and lab experiments to assess their effectiveness.
  • - Laccase from L1 demonstrated better degradation rates for compounds like estrone and estradiol valerate compared to commercial laccase, particularly when combined with the ABTS enhancer.
  • - Impressively, the L1 catalase-peroxidase outperformed commercial versions in degrading various estrogen compounds, showing significant potential for practical environmental cleanup applications while supporting experimental data through molecular dynamics simulations.
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This study showcased the antibiotic degradation abilities of laccase and catalase-peroxidase from Bacillus ligniniphilus L1, an extremophile, against 18 common antibiotics using computationally guided approach. Molecular docking and simulation identified six enzyme-antibiotic complexes for laccase and four for catalase-peroxidase, demonstrating significant binding affinity and stability. Enzyme activity assays corroborated computational results, indicating both enzymes could degrade all tested antibiotics with varying efficiencies.

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In this study, a novel oil-degrading strain Enterobacter kobei DH7 was isolated from petroleum-contaminated soil samples from the industrial park in Taolin Town, Lianyungang, China. The whole genome of the strain was sequenced and analyzed to reveal its genomic potential. The oil degradation and growth conditions including nitrogen, and phosphorus sources, degradation cycle, biological dosing, pH, and oil concentration were optimized to exploit its commercial application.

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Arachis hypogaea is an allotetraploid crop widely grown in the world. Wild relatives of genus Arachis are the rich source of genetic diversity and high levels of resistance to combat pathogens and climate change. The accurate identification and characterization of plant resistance gene, nucleotide binding site leucine rich repeat receptor (NLRs) substantially contribute to the repertoire of resistances and improve production.

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Among oral diseases, dental caries is one of the most frequent to affect human health. The current research work aimed to ascertain the antibacterial, anti-biofilm, and antioxidative potential of leaf extract against bacteria isolated from dental caries. Analysis for the presence of phytochemical compounds revealed compounds, such as tannins, steroids, phenolic compounds, and alkaloids, which were also confirmed by TLC and FTIR.

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