Publications by authors named "Syed Talha Liaqat"
Article Synopsis
- The World Health Organization has flagged SARS-CoV-2, especially the omicron variant, as a major concern due to its ability to evade vaccines through mutations in the spike protein.
- This study focuses on developing a vaccine that targets specific B- and T-cell epitopes of the virus, utilizing bioinformatics to identify potential candidates based on their immunogenicity and toxicity.
- The researchers constructed a Multi-Epitope Vaccine (MEV) and tested it in E. coli, showing promising immune responses which could offer a new strategy in the fight against SARS-CoV-2 infections.
J Biomol Struct Dyn
October 2022
Article Synopsis
- Dengue virus is a mosquito-borne disease that can lower platelets and white blood cell counts, with a focus on its essential replication proteins like NS3 and HSP70.
- To combat dengue, researchers are exploring the use of antivirals that can inhibit these proteins through methods like molecular docking and simulations to predict effective inhibitors.
- Ladanein, a flavonoid, emerged as a promising compound with the ability to inhibit dengue virus replication and HSP70, showcasing the potential of phytochemicals in anti-dengue strategies.
