Publications by authors named "Syed Suhaib Ahmed"
Article Synopsis
- The study focuses on developing solid lipid nanoparticles (SLNs) loaded with the chemotherapy drug irinotecan and the isoflavonoid daidzein, coated with materials like hyaluronic acid for targeted delivery to colon cancer cells.
- These nanoparticles were characterized for size, charge, and compatibility, revealing spherical shapes, high entrapment efficiency, and effective drug release patterns.
- In vitro and in vivo tests showed that these SLNs reduced cancer cell viability, promoted cell cycle arrest, and improved colon tissue structure, suggesting great potential for treating colon cancer.
Exploring the Potential Challenges for Developing Generic Orphan Drugs for Rare Diseases: A Survey of US and European Markets.
Vivek Reddy Murthannagari Ganesh Gonna Nandhi Krishnan Kavitha Viswabramhana Manu Chandu Thoti Jayachandraiah Praharsh Kumar Mandadhi Rajendra Syed Suhaib Ahmed
Value Health Reg Issues
May 2023
Objectives: The US Food and Drug Administration in 1983 and the European Union's European Medicines Agency in 2000 implemented the orphan drug development program for rare diseases. The study aimed to find the potential challenges encountered by generic companies in developing generics for rare diseases.
Methods: We performed a thematic analysis, which consists of qualitative and quantitative research.