Unravelling protein distributions within individual cells is vital to understanding their function and state and indispensable to developing new treatments. Here we present the Hybrid subCellular Protein Localiser (HCPL), which learns from weakly labelled data to robustly localise single-cell subcellular protein patterns. It comprises innovative DNN architectures exploiting wavelet filters and learnt parametric activations that successfully tackle drastic cell variability.
View Article and Find Full Text PDFIEEE Trans Image Process
May 2019
This paper addresses the problem of very large-scale image retrieval, focusing on improving its accuracy and robustness. We target enhanced robustness of search to factors such as variations in illumination, object appearance and scale, partial occlusions, and cluttered backgrounds -particularly important when search is performed across very large datasets with significant variability. We propose a novel CNN-based global descriptor, called REMAP, which learns and aggregates a hierarchy of deep features from multiple CNN layers, and is trained end-to-end with a triplet loss.
View Article and Find Full Text PDFIEEE Trans Pattern Anal Mach Intell
September 2017
Visual search and image retrieval underpin numerous applications, however the task is still challenging predominantly due to the variability of object appearance and ever increasing size of the databases, often exceeding billions of images. Prior art methods rely on aggregation of local scale-invariant descriptors, such as SIFT, via mechanisms including Bag of Visual Words (BoW), Vector of Locally Aggregated Descriptors (VLAD) and Fisher Vectors (FV). However, their performance is still short of what is required.
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