Creutzfeldt-Jakob disease: A comprehensive review of current understanding and research.

Creutzfeldt-Jakob Disease (CJD) is one of the sample prion diseases that have characteristic features of rapidly progressive neurodegenerative disease manifested by psychomotor changes, some of which include cognitive dysfunction, motor disorder, and behavioral abnormalities. In general, this brief review will assist in elucidating the clinical features and onset, causes, diagnostic challenges, and therapeutic possibilities of CJD. It is classified into sporadic, hereditary, and acquired forms, and affection is identified as linked to the different prion varieties and genetic profiles.

Comparing the Performance of Popular Large Language Models on the National Board of Medical Examiners Sample Questions.

Introduction: Large language models (LLMs) have transformed various domains in medicine, aiding in complex tasks and clinical decision-making, with OpenAI's GPT-4, GPT-3.5, Google's Bard, and Anthropic's Claude among the most widely used. While GPT-4 has demonstrated superior performance in some studies, comprehensive comparisons among these models remain limited.