Publications by authors named "Syed Hasan Jafri"

Article Synopsis
  • The management of stage III non-small cell lung cancer (NSCLC) has significantly advanced due to the addition of immunotherapy and targeted therapy.
  • The treatment options for this locally advanced cancer vary widely, including surgical and non-surgical methods, as well as chemo-immunotherapy, radiation, and targeted therapies where appropriate.
  • A multidisciplinary approach is crucial for diagnosing and treating stage III NSCLC effectively, reflecting the evolving landscape of this disease's management.
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Background: Major stressful life events have been shown to be associated with an increased risk of lung cancer, breast cancer and the development of various chronic illnesses. The stress response generated by our body results in a variety of physiological and metabolic changes which can affect the immune system and have been shown to be associated with tumor progression. In this study, we aim to determine if major stressful life events are associated with the incidence of head and neck or pancreatic cancer (HNPC).

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Immune checkpoint inhibitors (ICIs) have emerged as groundbreaking new therapies for a variety of solid tumors. ICIs stimulate the host immune system to attack cancer cells. However, this nonspecific immune activation can cause autoimmunity across multiple organ systems-this is referred to as an immune-related adverse event.

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