Characterization of Metronidazole, Clarithromycin and Amoxicillin Resistance Genes in Isolated from Gastroenteritis Patients.

Background: ()is a Gram-negative, microaerophilic, and spiral shape bacterium that resides inside the human stomach. The human stomach serves as its primary reservoir. Complaints about stomach complication due to infections are reported in the majority of populations around the globe.

The hydrodyanamics of gravity-driven vessel drainage of third order fluid using perturbation method.

In this work, tank drainage phenomena for in-compressible and isothermal fluid having unsteady fluid flow for third order fluid is studied. Analytical solution of the proposed problem is obtained using perturbation method subject to proper boundary conditions. No-slip condition is used because of fluid will have zero velocity relative to a solid boundary.

Neuroprotective effects of vitamin B1 on memory impairment and suppression of pro-inflammatory cytokines in traumatic brain injury.

Traumatic Brain Injury (TBI) remains one of the prevailing disorders that affect millions of people around the globe. There is a cascade of secondary attributes attached to TBI including excitotoxicity, axonal degeneration, neuroinflammation, oxidative stress, and apoptosis. Neuroinflammation is caused due to the activation of microglia along with pro-inflammatory cytokines.

FOXI3 pathogenic variants cause one form of craniofacial microsomia.

Craniofacial microsomia (CFM; also known as Goldenhar syndrome), is a craniofacial developmental disorder of variable expressivity and severity with a recognizable set of abnormalities. These birth defects are associated with structures derived from the first and second pharyngeal arches, can occur unilaterally and include ear dysplasia, microtia, preauricular tags and pits, facial asymmetry and other malformations. The inheritance pattern is controversial, and the molecular etiology of this syndrome is largely unknown.

Success of 14-day triple and quadruple therapy for the control of infections in Kohat district.

Introduction:: is an important medical pathogen present in more than half of the world’s population. Various treatment regimen are in use for the eradication of , but due to the emergence of antibiotic resistance, its management is a big issue for clinicians.

Methods:: In this study all suspected cases that had visited District Headquarters Hospital Kohat were considered for screening of infections.

A passive and programmable 3D paper-based microfluidic pump for variable flow microfluidic applications.

Paper has attracted significant attention recently as a microfluidic component and platform, especially in passive pumping devices due to its porous and uniform absorbing nature. Many investigations on 1D and 2D fluid flows were carried out. However, no experimental work has been reported on the three-dimensional effect in porous geometry to improve pumping characteristics in microchannels.

Cardiomyocyte Deletion of Exacerbates QT- and RR-Interval Prolongation in Mice.

Circadian rhythms are generated by cell autonomous circadian clocks that perform a ubiquitous cellular time-keeping function and cell type-specific functions important for normal physiology. Studies show inducing the deletion of the core circadian clock transcription factor in adult mouse cardiomyocytes disrupts cardiac circadian clock function, cardiac ion channel expression, slows heart rate, and prolongs the QT-interval at slow heart rates. This study determined how inducing the deletion of in adult cardiomyocytes impacted the electrophysiological phenotype of a knock-in mouse model for the arrhythmogenic long QT syndrome ( ).

Cocaine-Induced Headache: A Review of Pathogenesis, Presentation, Diagnosis, and Management.

Cocaine is a vasoactive substance, and its consumption has increased throughout the world. There are many neurological complications caused by chronic cocaine use, which include headache, aneurysmal formation, ischemic stroke, hemorrhagic stroke (subdural and subarachnoid hemorrhage), seizures, etc. Headache is one of the most common symptoms that appear after cocaine use.

When predictive analytics goes wrong: what can healthcare learn from Formula 1?

Predictive analytics refers to technology that uses patterns in large datasets to predict future events and inform decisions. This article considers the challenges of this technology and how these should be considered, before incorporating this technology into healthcare settings.

Comparison Of Biliary Stenting And Surgical Bypass In Palliative Management Of Irresectable Periampullary Carcinoma.

Background: Some 20-40% of the periampullary carcinoma is irresectable at the time of diagnosis. Biliary stenting and surgical bypass are commonly used palliative procedure. There is no consensus favouring one procedure over the other.

Depression In Myocardial Infarction Patients At Ayub Teaching Hospital Abbottabad.

Background: There is a considerably high prevalence of depression in post myocardial infarction (MI) patients. This study was designed with an aim to detect depression in patients with acute MI admitted to the CCU at Ayub Teaching Hospital Abbottabad..

Treatment of ingrown toe nail-comparison of phenolization after partial nail avulsion and partial nail avulsion alone.

Background: Ingrown toe nail is common problem presenting to the surgeon. Partial Nail avulsion only results in recurrence of the ingrown toe nail. The aim of this study was too see the effect of phenolization in preventing recurrence after partial nail avulsion.

Parents' opinion of quality of life (QOL) in Pakistani thalassaemic children.

Objective: To find out the physical, social, psychological life aspects and overall quality of life among thalassaemic children in Pakistan.

Methods: This cross-sectional study was done in ten Thalassaemia treatment centres in three major cities of Pakistan during the year 2007-08. The study population comprised of 221 thalassaemic children ranging from 4 to 12 years age brought for blood transfusion by their parents.

Concepts of homeopathy among general population in Karachi, Pakistan.

Objective: To explore the characteristics of patients and their gender influences concerning the use of homeopathic medicine, visiting both homeopathic and conventional medicine (allopathic) clinics.

Methods: This cross sectional study was carried out on 200 patients who attended private and public homeopathic and allopathic clinics or hospitals in Karachi using a pre-tested self-administered questionnaire. Data for demographic variables of frequencies and associations between variables were analyzed on SPSS version 12.

Knowledge and practices among the general practitioners of Karachi regarding dog bite management.

Objective: To find out the knowledge and practices among the general practitioners (GPs) of Karachi regarding dog bite management.

Methods: This cross sectional study was carried out in private and public Qlinics of Karachi using a pre-tested self-administered questionnaire. The study population was composed of 151 GPs with MBBS degree.

Lipoprotein (a) is associated with basal insulin levels in patients with type 2 Diabetes Mellitus.

Background: It has not been clearly established whether insulin resistance/deficiency leads directly to atherogenesis or through its association with other risk factors such as lipoprotein(a) [Lp(a)].

Objective: This project aimed at studying the association between basal insulin, lipids and lipoprotein(a) levels in patients with type 2 diabetes mellitus.

Methods: Fasting blood samples were analyzed for Insulin, Lipoprotein(a), total cholesterol (TC), triglycerides (TG), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), glucose and glycosylated hemoglobin (HbA1c) levels in 60 patients with type 2 Diabetes Mellitus (DM) and 28 healthy subjects.

Usefulness of standard treadmill stress testing in women.

Objective: To determine the usefulness of stress test to detect coronary artery disease in women in local population.

Methods: Patients coming for stress test were evaluated clinically and 835 patients were enrolled, 69.6% were men and 30.

Two-port laparoscopic cholecystectomy--a new technique.

Laparoscopic cholecystectomy is now the procedure of choice in all the gall bladder diseases and there is increase in the skills of surgeons with newer equipment. Normally the laparoscopic cholecystectomy is performed by using four ports or three ports. Two ports laparoscopic cholecystectomy is rarely performed as it demands greater expertise and skills.