Publications by authors named "Syed Douhath"

Article Synopsis
  • Polycystic ovary syndrome (PCOS) diagnosis commonly involves indicators such as irregular periods, high androgen levels, and ovarian structure; however, the impact of frequent periods (polymenorrhoea) and partial PCOS cases remains underexplored.
  • In a study with over 9,600 women, those diagnosed with PCOS, especially with hyperandrogenism or oligomenorrhoea, displayed higher body mass index (BMI), elevated blood glucose, and lipid levels compared to healthy women, while insulin resistance levels were notably higher across the board.
  • The polymenorrhoea subgroup showed lower BMI and testosterone levels but shared similar metabolic characteristics with women experiencing oligomenorrhoea
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Purpose: The abnormal activation of the sonic hedgehog (SHH) signaling pathway is responsible for the progression of several types of cancers including Gastric Cancer (GC). SHH has been associated with the activation of different signaling pathways. Therefore, in this study, we investigated messenger RNA (mRNA) and protein expression of SHH in gastric malignancies and possible correlation with various clinicopathological parameters.

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Objective: Polycystic ovarian syndrome (PCOS) is a clinically heterogeneous endocrine disorder affecting up to 4-8% of women of reproductive age. The aim of this study was to evaluate the presence of microalbuminuria in women with PCOS and study its correlation with the various metabolic, clinical, and hormonal parameters.

Materials And Methods: A cross-sectional study involving 69 PCOS women was carried out in a tertiary care center hospital.

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